PMID: 4895217Mar 1, 1969Paper

Synthesis of phage-specific alpha- and beta-glucosyl transferases directed by T-even DNA in vitro

Proceedings of the National Academy of Sciences of the United States of America
L M Gold, M Schweiger

Abstract

-Bacteriophage T4 DNA, when added to a ribonucleic acid- and protein-synthesizing system from uninfected Escherichia coli, directed the in vitro synthesis of virus-specific glucosyl transferases. The T4-specific alpha- and beta-glucosyl transferases are synthesized in vivo early after infection, and function to glucosylate the hydroxymethylcytosine residues of phage DNA. The in vitro glucosyl transferase synthesis was dependent upon transcription of T4 DNA, as well as upon protein synthesis. DNA from T4 mutants unable to induce glucosyl transerases failed to induce enzyme formation in vitro, although protein synthesis was unimpaired.

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Citations

Jan 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·J R MurphyS T de Borms
Jan 7, 1997·Proceedings of the National Academy of Sciences of the United States of America·L GoldY Wu
Feb 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·E KaltschmidtM Nomura
May 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·N H Scherberg, S B Weiss
Apr 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·E H McConkey
Aug 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·M Schweiger, L M Gold
Feb 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·J M Wilhelm, R Haselkorn
Feb 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·M E Morris, H Gould
Apr 27, 2011·Proceedings of the National Academy of Sciences of the United States of America·Shigeru DeguchiKoki Horikoshi
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Apr 16, 2019·Frontiers in Microbiology·Kiersten FlodmanShuang-Yong Xu
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Dec 1, 1970·Journal of Virology·P Herrlich, M Schweiger

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