Synthesis of Schiff base-Based 1,2,4-Oxadiazole Derivative as Fluorescence Turn-On Sensor for High Selectivity of Pb(2.)

Journal of Fluorescence
Wei LiuHaibo Wang

Abstract

A new probe based on oxadiazole derivative (OXD) containing Schiff base moiety was synthesised as fluorescence turn-on sensor S1 . Furthermore, its fluorescents spectra (FS) result demonstrate that S1 selectively senses bivalent lead ion (Pb(2+)) in HEPES buffer solution (10 mM, pH = 7.0,DMF-H2O, 9:1, v/v), so S1 was a viable candidate as fluorescent receptor for a new Pb(2+) sensor. And the results of fluorescent spectral titration showed this sensor formed 1:1complex with Pb(2+).

References

Jul 26, 2008·Chemical Reviews·Elizabeth M Nolan, Stephen J Lippard
Sep 2, 2009·The Journal of Organic Chemistry·John Kallikat AugustinePadma Alagarsamy
Sep 29, 2009·Biotechnology Letters·Yue-Jun FuAi-Hua Liang
Dec 21, 2011·Chemical Society Reviews·Ha Na KimJuyoung Yoon

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