PMID: 9537034Jan 1, 1980Paper

Synthesis of secretory component by rat hepatocytes in culture

Scandinavian Journal of Immunology
J L ZevenbergenJ P Vaerman

Abstract

Normal rat hepatocytes were isolated and cultivated in vitro. Synthesis of secretory component was demonstrated by its accumulation in the culture medium, as measured by radioimmunoassay; by incorporation of 14C-leucine in the protein specifically precipitated with anti-secretory component antiserum; and by a positive precipitin reaction of concentrated culture medium with the same antiserum. The results explain the high levels of secretory component found in rat bile and render plausible a mechanism of hepatic IgA transfer involving secretory component as the hepatocyte membrane receptor for polymeric IgA.

References

Jan 1, 1978·Advances in Experimental Medicine and Biology·P Brandtzaeg, E Savilahti
Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M M FisherB J Underdown
Jan 1, 1978·Scandinavian Journal of Immunology·U HopfK H Meyer zum Büschenfelde
Feb 1, 1978·The Journal of Experimental Medicine·E OrlansJ Hall
Mar 1, 1978·The Journal of Experimental Medicine·I Lemaître-CoelhoJ P Vaerman
Jun 1, 1978·The Journal of Experimental Medicine·S S CragoJ Mestecky
Aug 1, 1977·European Journal of Immunology·I Lemaître-CoelhoJ P Vaerman
Jan 1, 1966·International Archives of Allergy and Applied Immunology·P J McConahey, F J Dixon
Jan 1, 1968·Advances in Immunology·T B Tomasi, J Bienenstock
Jul 1, 1970·The Journal of Clinical Investigation·W R BrownK Ishizaka
Feb 1, 1972·Proceedings of the Society for Experimental Biology and Medicine·S S OgraT B Tomasi
Jan 1, 1965·The Journal of Experimental Medicine·T B TOMASIR A PRENDERGAST

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Citations

Dec 1, 1981·Journal of Steroid Biochemistry·D A Sullivan, C R Wira
Apr 1, 1981·Molecular Immunology·D J SockenB J Underdown
Jun 30, 1983·Annals of the New York Academy of Sciences·C R WiraC P Sandoe
Jun 30, 1983·Annals of the New York Academy of Sciences·D L Delacroix, J P Vaerman
Jan 1, 1989·Immunological Investigations·W R Brown, T M Kloppel
Jan 1, 1981·Scandinavian Journal of Immunology·H TolleshaugK Holte
Nov 1, 1986·Scandinavian Journal of Immunology·U I DahlgrenL A Hanson
May 1, 1989·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·W R Brown, T M Kloppel
Sep 1, 1986·Scandinavian Journal of Immunology·U I DahlgrenC Svanborg Edén
Mar 1, 1983·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J Rank, I D Wilson
Nov 1, 1983·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D L DelacroixJ P Vaerman

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