Synthesis of Water-Soluble Ag2 S Quantum Dots with Fluorescence in the Second Near-Infrared Window for Turn-On Detection of Zn(II) and Cd(II)

Analytical Chemistry
Qian WuZhixun Zhang

Abstract

The second near-infrared window emission (1.0-1.7 μm, NIR-II) has received extensive attention with the advantages of negligible tissue scattering, reduced autofluorescence, and less background noise. Here a novel analysis platform based on quantum dots (QDs) for highly selective detection of Zn2+ and Cd2+ with an enhanced NIR-II fluorescence is reported for the first time. We have developed a facile two-step route to synthesize the water-soluble Ag2S QDs, constituting of a green hydrothermal process and followed surface ligands exchange. Surface passivation was proposed to be the mechanism for the enhanced fluorescence. The added Zn2+ or Cd2+ could react with the surface thioglycollic acid to form Zn-thiol or Cd-thiol complex passivation shell, which restored surface defects and suppressed nonradiative recombination pathway. The detection platform exhibited a linear relationship between the ion concentrations and enhanced fluorescence and had a detection limit as low as 760 nM for Zn2+ and 546 nM for Cd2+ at pH = 7.4. Furthermore, the as-synthesized Ag2S QDs showed good robustness in real sample matrix and were demonstrated to be able to detect exogenous Zn(II) in cells. These properties suggest potential applications of detec...Continue Reading

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Citations

Mar 28, 2018·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zhong-Xia WangWei Wang
Nov 4, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Karishma BhardwajSudarsan Tamang
Jun 13, 2021·Advanced Materials·Caiping DingXiaoyuan Chen
Jul 21, 2021·Chemical Reviews·W Russ AlgarHyungki Kim
Jun 12, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Mingxi YangBai Yang
Jun 5, 2020·ACS Applied Materials & Interfaces·Rong HuYunhui Yang

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