Synthesis, thermal and surface activity of cationic single chain metal hybrid surfactants and their interaction with microbes and proteins

Soft Matter
Gurpreet KaurVinod K Aswal

Abstract

A series of water-soluble metal functionalized surfactants have been prepared using commercially available surfactant cetyl pyridinium chloride and transition metal salts. These complexes were characterized in the solid state by elemental analysis, FTIR, 1H NMR and thermogravimetric analysis. The interfacial surface activity and aggregation behaviour of the metallosurfactants were analysed through conductivity, surface tension and small angle neutron scattering measurements. Our results show that the presence of metal ions as co-ions along with counter ions favours micellization at a low critical micellization concentration (CMC). Small angle neutron scattering revealed that the metallomicelles are of a prolate ellipsoidal shape and exhibit strong counterion binding. This article further describes the interaction of the metallosurfactants with transport protein Bovine Serum Albumin (BSA) using different spectroscopic techniques. A spectroscopic study was used to study the binding, interaction and quenching mechanism of BSA with the metallosurfactants. Gel electrophoresis (SDS-PAGE) and circular dichroism (CD) investigated the structural and conformational changes produced in BSA due to the metallosurfactants. The results indica...Continue Reading

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Citations

Sep 24, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Bunty SharmaGanga Ram Chaudhary
Jun 20, 2019·International Journal of Molecular Sciences·Tomasz JanekŻaneta Czyżnikowska

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Methods Mentioned

BETA
small angle neutron scattering
circular dichroism
electrophoresis
SANS
neutron scattering
Fluorescence

Software Mentioned

Emplura

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