Apr 23, 2020

Genomic regions linked to soft sweeps approximate neutrality when inferring population history from site pattern frequencies

BioRxiv : the Preprint Server for Biology
Nathan Scott Harris, A. R. Rogers

Abstract

Recent studies have suggested that selection is widespread throughout the genome and largely uncompensated for in inferences of population history. To address this potential issue, we estimated site pattern frequencies for neutral and selection associated areas of the genome. There are notable differences in these frequencies between neutral regions and those affected by selection. However, these differences have relatively small effects when inferring population history.

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