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Synthesizing Combination Therapies for Evolutionary Dynamics of Disease for Nonlinear Pharmacodynamics

bioRxiv

Sep 21, 2014

Vanessa JonssonRichard M. Murray

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Abstract

Our previous results proposed an iterative scalable algorithm for the systematic design of sparse, small gain feedback strategies that stabilize the evolutionary dynamics of a generic disease model with linear pharmacodynamics. In this manuscript, we use piecewise linear approximations ...read more

Mentioned in this Paper

Pharmacodynamics
Drug Effect
Combination Drug Therapy
Disease Theory of Alcohol or Other Drug Use, Abuse and Dependence
Pharmacodynamic Aspects
Pharmacological Drug Effects
Disease Model
4
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  • Synthesizing Combination Therapies for Evolutionary Dynamics of Disease for Nonlinear Pharmacodynamics

    bioRxiv

    Sep 21, 2014

    Vanessa JonssonRichard M. Murray

    PMID: 990009480

    DOI: 10.1101/009480

    Abstract

    Our previous results proposed an iterative scalable algorithm for the systematic design of sparse, small gain feedback strategies that stabilize the evolutionary dynamics of a generic disease model with linear pharmacodynamics. In this manuscript, we use piecewise linear approximations ...read more

    Mentioned in this Paper

    Pharmacodynamics
    Drug Effect
    Combination Drug Therapy
    Disease Theory of Alcohol or Other Drug Use, Abuse and Dependence
    Pharmacodynamic Aspects
    4

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