Synthetic approaches to the 2013 new drugs

Bioorganic & Medicinal Chemistry
Hong X DingChristopher J O'Donnell

Abstract

New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition and also serve as leads for designing future new drugs. This annual review covers the synthesis of twenty-four NCEs that were approved for the first time in 2013 and two 2012 drugs which were not covered during the previous edition of this review.

References

Feb 2, 1996·Journal of Medicinal Chemistry·D R MagninC P Ciosek
Feb 18, 2004·Mini Reviews in Medicinal Chemistry·Jin Li, Kevin K-C Liu
Dec 8, 2004·Mini Reviews in Medicinal Chemistry·Kevin K-C LiuSubas Sakya
Jun 7, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Sonu S SinghVidya B Lohray
Dec 27, 2005·Mini Reviews in Medicinal Chemistry·Jin LiSubas Sakya
Apr 14, 2007·Mini Reviews in Medicinal Chemistry·Subas M SakyaKevin K-C Liu
Jan 29, 2008·Mini Reviews in Medicinal Chemistry·Kevin K-C LiuJin Li
Sep 11, 2008·The Journal of Pharmacology and Experimental Therapeutics·Marc IglarzMartine Clozel
Nov 18, 2008·Cancer Research·Gail D Lewis PhillipsMark X Sliwkowski
Dec 17, 2008·Mini Reviews in Medicinal Chemistry·Kevin K-C LiuJin Li
Jan 28, 2009·Antimicrobial Agents and Chemotherapy·Tse-I LinKenneth Simmen
Jan 22, 2010·Mini Reviews in Medicinal Chemistry·Kevin K-C LiuJin Li
May 1, 2010·Expert Opinion on Drug Metabolism & Toxicology·Jamie L McCall, Michael W DeGregorio
Jul 10, 2010·Proceedings of the National Academy of Sciences of the United States of America·Lee A HonigbergJoseph J Buggy
Mar 12, 2011·Expert Opinion on Investigational Drugs·Ralph T SchermulyHossein Ardeschir Ghofrani
Mar 23, 2011·Expert Opinion on Investigational Drugs·Jan Tack, Pieter Janssen
Jul 8, 2011·Bioorganic & Medicinal Chemistry Letters·John C StellwagenDavid E Uehling
Oct 25, 2011·Journal of Clinical Pharmacy and Therapeutics·S-H HsiaoT-J Wu
Feb 2, 2012·Annals of the Rheumatic Diseases·Christian BeyerJörg H W Distler
Apr 23, 2013·Drugs·Shelley Elkinson, Lily P H Yang
May 24, 2013·Drugs·Rosselle Dungo, Emma D Deeks
Jul 13, 2013·Drugs·Cameron J M Wright, Paul L McCormack
Oct 9, 2013·Journal of Medicinal Chemistry·Lucienne Juillerat-Jeanneret
Oct 26, 2013·Drugs·Andrew Gibb, Lily P H Yang
Nov 20, 2013·Drugs·Trina Patel, Sohita Dhillon
Dec 4, 2013·Drugs·Trina Patel, Kate McKeage
Feb 14, 2014·Drugs of Today·R TalwaniZ Temesgen
Feb 14, 2014·Drugs of Today·A I GraulM Stringer
Feb 15, 2014·Expert Review of Clinical Pharmacology·Rajnish MagoMichael E Thase
Mar 4, 2014·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Alexander M Menzies, Georgina V Long
Mar 29, 2014·Expert Opinion on Pharmacotherapy·Santiago Perez-Lloret, Marcelo Merello
Jul 16, 2014·Cancer Cell·Ryan M Young, Louis M Staudt

❮ Previous
Next ❯

Citations

Feb 19, 2016·European Journal of Medicinal Chemistry·Davir González-CalderónAydeé Fuentes-Benítes
Feb 9, 2016·Journal of Natural Products·David J Newman, Gordon M Cragg
Apr 20, 2017·Journal of Medicinal Chemistry·Andrew C FlickChristopher J O'Donnell
Jun 11, 2016·Organic & Biomolecular Chemistry·Alexandria P TaylorOlugbeminiyi Fadeyi
Dec 13, 2016·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Shubo DongHanyue Yang
Nov 4, 2020·Expert Opinion on Biological Therapy·Yutaka Matsuda, Brian A Mendelsohn
Jan 23, 2021·RSC Medicinal Chemistry·Yan YinYangbo Feng
Mar 31, 2021·Journal of Medicinal Chemistry·Andrew C FlickChristopher J O'Donnell
Nov 5, 2020·Journal of the American Chemical Society·Roser Marín-VallsPere Clapés
Apr 6, 2018·Journal of Medicinal Chemistry·Andrew C FlickChristopher J O'Donnell
Sep 15, 2017·Chemical Reviews·Jiajie FengMichael J Krische
Apr 3, 2019·Journal of Medicinal Chemistry·Andrew C FlickChristopher J O'Donnell
Apr 28, 2020·Journal of Medicinal Chemistry·Andrew C FlickChristopher J O'Donnell
Oct 9, 2021·Journal of Medicinal Chemistry·Cecilia C Ayala-AguileraAsier Unciti-Broceta

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Bioorganic & Medicinal Chemistry
Hong X DingChristopher J O'Donnell
Bioorganic & Medicinal Chemistry
Hong X DingChristopher J O'Donnell
Bioorganic & Medicinal Chemistry
Kevin K-C LiuHong X Ding
Mini Reviews in Medicinal Chemistry
Kevin K-C LiuJin Li
Bioorganic & Medicinal Chemistry
Kevin K-C LiuJin Li
© 2021 Meta ULC. All rights reserved