Synthetic biology advances for pharmaceutical production

Current Opinion in Biotechnology
Rainer Breitling, Eriko Takano

Abstract

Synthetic biology enables a new generation of microbial engineering for the biotechnological production of pharmaceuticals and other high-value chemicals. This review presents an overview of recent advances in the field, describing new computational and experimental tools for the discovery, optimization and production of bioactive molecules, and outlining progress towards the application of these tools to pharmaceutical production systems.

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Citations

Aug 12, 2015·FEMS Microbiology Letters·Richard KelwickRichard P Bowater
Jan 26, 2017·Chemical Communications : Chem Comm·Judith HavemannManuela Tosin
Dec 20, 2017·Journal of Industrial Microbiology & Biotechnology·Alejandro PeñaRainer Breitling
Apr 5, 2018·FEMS Yeast Research·Tatiana M Souza-MoreiraAnastasia Krivoruchko
Apr 15, 2020·Marine Drugs·Luisa AlbaranoMaria Costantini
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Sep 13, 2017·Frontiers in Cell and Developmental Biology·Angela Re
Aug 15, 2017·Scientometrics·Philip ShapiraJan Youtie
Feb 7, 2021·Biotechnology Advances·Zhengshan LuoJingwen Zhou
Jun 25, 2015·ACS Synthetic Biology·Matthias ChristenBeat Christen

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Methods Mentioned

BETA
biosensing

Software Mentioned

Retropath
antiSMASH

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