PMID: 2092946Dec 1, 1990Paper

Synthetic cephalosporins. VII. Synthesis and antibacterial activity of 7-[(Z)-2-(2-aminothiazol-4-yl)-2-(3-(3-hydroxy-4-pyridon-1-yl)-3- carboxypropoxyimino)acetamido]-3-(1,2,3-thiadiazol-5-yl)-thiomethyl-3- cephem-4-carboxylic acid and its related compounds

Chemical & Pharmaceutical Bulletin
K SakagamiM Hatanaka

Abstract

Synthesis and antibacterial activity of 7-[(Z)-2-(2-aminothiazol-4-yl)-2-(3-(3-hydroxy-4-pyridon-1-y l)-3- carboxypropoxyimino)acetamido]-3-(1,2,3-thiadiazol-5-yl)thio methyl-3-cephem-4-carboxylic acid (12a) and its related compounds are described. Compound 12a exhibited excellent antibacterial activity against gram-negative bacteria, including Pseudomonas aeruginosa.

Citations

Apr 4, 2017·Chemistry : a European Journal·Johannes P SchmidtBernhard Breit
Jan 21, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Shakir Mahmood Alwan
Mar 12, 2021·Bioorganic & Medicinal Chemistry Letters·Zhengwu ShenHongzhu Bian

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