Synthetic MRI of the Knee: Phantom Validation and Comparison with Conventional MRI

Radiology
Neil M KumarJan Fritz

Abstract

Purpose To test the hypothesis that synthetic MRI of the knee generates accurate and repeatable quantitative maps and produces morphologic MR images with similar quality and detection rates of structural abnormalities than does conventional MRI. Materials and Methods Data were collected prospectively between January 2017 and April 2018 and were retrospectively analyzed. An International Society for Magnetic Resonance in Medicine-National Institute of Standards and Technology phantom was used to determine the accuracy of T1, T2, and proton density (PD) quantification. Statistical models were applied for correction. Fifty-four participants (24 men, 30 women; mean age, 40 years; range, 18-62 years) underwent synthetic and conventional 3-T MRI twice on the same day. Fifteen of 54 participants (28%) repeated the protocol within 9 days. The intra- and interday agreements of quantitative cartilage measurements were assessed. Contrast-to-noise (CNR) ratios, image quality, and structural abnormalities were assessed on corresponding synthetic and conventional images. Statistical analyses included the Wilcoxon test, χ2 test, and Cohen Kappa. P values less than or equal to .01 were considered to indicate a statistically significant differe...Continue Reading

References

Nov 1, 1994·Journal of Digital Imaging·S J GarnierJ W Gault
Feb 21, 2003·Journal of Magnetic Resonance Imaging : JMRI·Cynthia F MaierHollis G Potter
Aug 9, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Greg J StaniszR Mark Henkelman
Jan 30, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Felix EcksteinErika Schneider
Feb 28, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J B M WarntjesP Lundberg
Jul 31, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J B M WarntjesP Lundberg
Nov 19, 2013·Journal of Magnetic Resonance Imaging : JMRI·Jens-Peter KühnScott Reeder
Nov 7, 2015·Journal of the American College of Radiology : JACR·Michael J TuiteBarbara N Weissman
Oct 21, 2016·Skeletal Radiology·Sven NebelungDaniel Truhn
Feb 6, 2017·Journal of Biomechanics·Anthony A GattiMonica R Maly
Sep 16, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Octavia BaneBachir Taouli
Oct 7, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Andrew F MillsHernan Jara

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Citations

Feb 7, 2020·Journal of Magnetic Resonance Imaging : JMRI·Yadong CuiMin Chen
May 21, 2020·Medical Physics·Siamak P Nejad-DavaraniCarri K Glide-Hurst
Feb 4, 2021·AJR. American Journal of Roentgenology·Jan FritzFilippo Del Grande
Feb 5, 2021·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Tomoyuki FujiokaUkihide Tateishi
Sep 22, 2021·Seminars in Musculoskeletal Radiology·Meghan SahrDarryl B Sneag
Jul 1, 2021·Investigative Radiology·Iman Khodarahmi, Jan Fritz

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