Abstract
The purpose of the present study was to evaluate whether an IVF protein supplement prepared from human serum albumin (HSA) and human globulins would retain performance characteristics equivalent to those reported for the commercial plasma expanders, Plasmatein (Alpha Therapeutics, Los Angeles, California) and Plasmanate (Cutter Biological, Miles Inc., Elkhart, Indiana). Pronuclear-stage human embryos were randomly divided and cultured in human tubal fluid medium (HTF) supplemented with either HSA (5 mg/mL) or Plasmatein (10%, v/v; 5 mg/ml) as a means of indirectly assessing the effect alpha- and beta-globulins have on embryonic development. Those results coupled with the known composition characteristics of Plasmatein were used as the starting basis to formulate test lots of synthetic serum substitute (SSS). Significantly (P < 0.05) more of the human embryos cultured in Plasmatein supplemented medium reached the four-cell or greater stage by 40 hr postinsemination than a comparable group cultured in HSA alone. Lot 1 of SSS, formulated with HSA (84% of total protein) and human globulins (16% of total protein) and an aqueous lipoprotein fraction derived from human plasma (Excyte IV; Miles Diagnostics, Kankakee, Illinois), produce...Continue Reading
References
Oct 1, 1992·Fertility and Sterility
Feb 1, 1992·Journal of Assisted Reproduction and Genetics·M C LéveilléN Tanphaichitr
Apr 1, 1992·Infusionstherapie und Transfusionsmedizin·M Burnouf-RadosevichJ J Huart
Jul 1, 1990·Human Reproduction·G T WaitesP L Wood
Apr 1, 1990·Human Reproduction·C StaessenA C Van Steirteghem
Aug 1, 1989·Human Reproduction·M J Ashwood-SmithR G Edwards
Aug 1, 1986·American Journal of Reproductive Immunology and Microbiology : AJRIM·J R Oksenberg, C Brautbar
Mar 1, 1986·Transfusion·M A WellsG V Quinnan
Feb 1, 1987·Journal of in Vitro Fertilization and Embryo Transfer : IVF·J M ShawJ F Hennessey
Aug 1, 1987·Journal of in Vitro Fertilization and Embryo Transfer : IVF·P ClamanM L Taymor
Aug 1, 1986·Journal of in Vitro Fertilization and Embryo Transfer : IVF·C M Caro, A Trounson
Jan 1, 1985·Annals of the New York Academy of Sciences·P QuinnC Kirby
Jan 1, 1985·Fertility and Sterility·B ShirleyG Fort
Feb 1, 1972·Contraception·J LippesW R Bartholomew
Nov 1, 1981·Fertility and Sterility·J LippesR Lucero
Nov 1, 1984·Fertility and Sterility·Y MenezoD Perrone
Jan 1, 1984·Fertility and Sterility·P C LeungI Johnston
Jun 1, 1984·Fertility and Sterility·P Kemeter, W Feichtinger
Apr 1, 1994·Fertility and Sterility·T B Pool, J E Martin
Dec 1, 1994·Biology of Reproduction·M Murray, S M Messinger
Aug 1, 1993·Fertility and Sterility·A DokrasD H Barlow
Mar 1, 1993·Biology of Reproduction·M K Murray
Jan 1, 1993·Journal of Assisted Reproduction and Genetics·A AdlerJ Cohen
Jul 1, 1957·Vox Sanguinis·J H HINKF F JOHNSON
Citations
May 1, 1996·Journal of Assisted Reproduction and Genetics·J FrasorR G Rawlins
Oct 1, 1996·Obstetrics and Gynecology·K F MillerT Falcone
Jun 1, 2001·Fertility and Sterility·N A CekleniakC Racowsky
Jan 1, 1997·Fertility and Sterility·K J DuganS L Padilla
Jun 9, 1999·Fertility and Sterility·M C Lu
Apr 24, 2003·Reproductive Biomedicine Online·M BungumL Bungum
Jun 10, 2004·Journal of Assisted Reproduction and Genetics·Jennifer E GravesWilliam R Boone
Dec 1, 2004·Journal of Assisted Reproduction and Genetics·Dalit Ben-YosefYuval Yaron
Aug 1, 1996·American Journal of Reproductive Immunology : AJRI·E G Schneider, C C Hayslip
Jan 28, 2005·Journal of Assisted Reproduction and Genetics·Marc J G Van den BerghMichael Hohl
Sep 28, 2014·Journal of Assisted Reproduction and Genetics·Dean E MorbeckDietrich Matern
Jan 17, 2009·Human Reproduction·Marius MeintjesJames D Madden
Feb 15, 2002·Human Fertility : Journal of the British Fertility Society·Thomas G. McEvoyJohn J. Robinson
Feb 7, 2016·Fertility and Sterility·Jason E SwainGary D Smith
Nov 28, 2015·Reproductive Biomedicine Online·Jianying HuangHongshan Ge
Jan 13, 2016·Journal of Assisted Reproduction and Genetics·Aila CoelloAna Cobo
Mar 24, 2012·Chemosphere·Yusuke IwasakiHiroyuki Nakazawa
Oct 13, 2007·Theriogenology·K MooreA Niasari-Naslaji
Jul 25, 2015·Human Reproduction Update·Petra L Wale, David K Gardner
Jan 4, 2013·Reproduction in Domestic Animals = Zuchthygiene·E NestleP Comizzoli
Sep 8, 2015·Journal of Assisted Reproduction and Genetics·Jolene FredricksonDean E Morbeck
Mar 17, 2017·Systems Biology in Reproductive Medicine·Alessandra A VirequeAna Carolina J Sá Rosa-E-Silva
Apr 18, 2018·Current Opinion in Obstetrics & Gynecology·Diego Marin, Richard T Scott
Mar 3, 2012·Clinical and Experimental Reproductive Medicine·Jeong YoonJin-Ho Lim
Dec 31, 2014·Endocrine Reviews·George A ThouasDavid K Gardner
Jul 14, 2017·Scientific Reports·Elisa GiacominiPaola Viganò
Feb 28, 2019·Stem Cell Research & Therapy·Wojciech ZakrzewskiZbigniew Rybak
Jun 15, 2017·Journal of Developmental Origins of Health and Disease·D K Gardner, R L Kelley
Nov 5, 2019·Reproductive Biomedicine Online·Michael L Reed, Al-Hasen Said
Jan 15, 2021·Zygote : the Biology of Gametes and Early Embryos·Sam Zarbakhsh