PMID: 8946631Nov 1, 1996Paper

Syphilis and the risk of penis cancer

Sexually Transmitted Diseases
M FrischM Melbye

Abstract

Until recently, syphilis was considered a major cause of penis cancer. The possible role of syphilis was discarded without much debate with the detection of certain of human papillomaviruses centrally involved in the etiology of penis cancer. To reevaluate the association between syphilis and penis cancer by using truly population-based cancer and syphilis data and to generate a more sound basis for judging the possible role of syphilis in the etiology of penis cancer. Patients with epidermoid cancer of the penis, totalling 1,523, were diagnosed and reported to the Danish Cancer Registry from 1943 to 1990. Through linkage with the Danish Syphilis Registry, the impact of prior syphilis infection was evaluated in a case-control design using patients with colon cancer or stomach cancer as controls. Depending on the criteria used to assess prior syphilis status, 3% to 5% of patients with penis cancer had had syphilis before the cancer diagnosis. The corresponding proportions were 2% to 4% among patients with colon cancer and 2% to 5% among patients with stomach cancer. Logistic regression showed that patients with penis cancer did not have a syphilis history significantly more often than control cancer patients. Syphilis should be ...Continue Reading

References

Jan 15, 1992·American Journal of Epidemiology·J R DalingN S Weiss
Feb 20, 1991·International Journal of Cancer. Journal International Du Cancer·L A BrintonS Dawsey
Nov 21, 1987·British Medical Journal·D HellbergS Nilsson
Mar 1, 1971·British Journal of Cancer·R Schmauz, D K Jain
Apr 1, 1994·International Journal of Epidemiology·A M MichalekB B Metzger
Jan 6, 1993·Journal of the National Cancer Institute·C MadenJ R Daling
Dec 2, 1995·BMJ : British Medical Journal·M FrischM Melbye
Oct 1, 1963·Cancer·O G DODGE, C A LINSELL
Dec 1, 1907·Annals of Surgery·J D Barney

❮ Previous
Next ❯

Citations

May 26, 2004·The Nursing Clinics of North America·R Craig Stotts
Sep 15, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Marc T GoodmanYurii B Shvetsov

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.