Systematic analysis of ECG predictors of sinus rhythm maintenance after electrical cardioversion for persistent atrial fibrillation

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Theo LankveldUlrich Schotten

Abstract

Electrical cardioversion (ECV) is one of the rhythm control strategies in patients with persistent atrial fibrillation (AF). Unfortunately, recurrences of AF are common after ECV, which significantly limits the practical benefit of this treatment in patients with AF. The objectives of this study were to identify noninvasive complexity or frequency parameters obtained from the surface electrocardiogram (ECG) to predict sinus rhythm (SR) maintenance after ECV and to compare these ECG parameters with clinical predictors. We studied a wide variety of ECG-derived time- and frequency-domain AF complexity parameters in a prospective cohort of 502 patients with persistent AF referred for ECV. During 1-year follow-up, 161 patients (32%) maintained SR. The best clinical predictor of SR maintenance was antiarrhythmic drug (AAD) treatment. A model including clinical parameters predicted SR maintenance with a mean cross-validated area under the receiver operating characteristic curve (AUC) of 0.62 ± 0.05. The best single ECG parameter was the dominant frequency (DF) on lead V6. Combining several ECG parameters predicted SR maintenance with a mean AUC of 0.64 ± 0.06. Combining clinical and ECG parameters improved prediction to a mean AUC of ...Continue Reading

References

Nov 24, 1999·The American Journal of Cardiology·I C Van GelderH J Crijns
Dec 6, 2002·The New England Journal of Medicine·Isabelle C Van GelderUNKNOWN Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation Study Group
Feb 6, 2004·Journal of Cardiovascular Electrophysiology·Andreas BollmannHelmut U Klein
Jul 31, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Andreas BollmannS Bertil Olsson
Oct 16, 2008·JAMA : the Journal of the American Medical Association·Sheba AhmedUNKNOWN CONVERT Investigators
Oct 24, 2008·Physiological Measurement·Raúl Alcaraz, José Joaquín Rieta
Apr 3, 2009·The Canadian Journal of Cardiology·Michalis EfremidisFotios Kardaras
Apr 17, 2009·Physiological Measurement·Raúl Alcaraz, José Joaquín Rieta
Aug 25, 2009·Journal of Electrocardiology·Roger AbächerliLukas Kappenberger
Sep 30, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·A John CammUNKNOWN ESC Committee for Practice Guidelines
Jan 21, 2011·Physiological Reviews·Ulrich SchottenAndreas Goette
May 25, 2011·Pacing and Clinical Electrophysiology : PACE·Raúl AlcarazJosé J Rieta
Mar 17, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Ulrich SchottenStef Zeemering
Jun 23, 2012·Circulation. Arrhythmia and Electrophysiology·Hemantha KoduriRishi Arora
Jan 1, 2014·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Tomos E WaltersJonathan M Kalman
Feb 19, 2014·European Heart Journal·Stanley NattelA John Camm
Feb 22, 2014·International Journal of Cardiology·Harry J G M CrijnsJean-Yves Le Heuzey
May 20, 2014·Heart·Theo A R LankveldUlrich Schotten
Aug 15, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Pietro BonizziUlrich Schotten

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Citations

Feb 2, 2016·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Damian P Redfearn, Javad Hashemi
Jan 5, 2018·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Dipak KotechaPaulus Kirchhof
Dec 17, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·José María Lillo-CastellanoDavid Filgueiras-Rama

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