Systematic and Multidisciplinary Evaluation of Fibromuscular Dysplasia Patients Reveals High Prevalence of Previously Undetected Fibromuscular Dysplasia Lesions and Affects Clinical Decisions: The ARCADIA-POL Study.

Hypertension
Ewa Warchol-CelinskaAndrzej Januszewicz

Abstract

Fibromuscular dysplasia (FMD), regarded as a generalized vascular disease, may affect all vascular beds and may result in arterial stenosis, occlusion, aneurysm, or dissection. It has been proposed to systematically evaluate all vascular beds in patients with FMD, regardless of initial FMD involvement. However, the impact of this approach on clinical decisions and on management is unknown. Within the prospective ARCADIA-POL study (Assessment of Renal and Cervical Artery Dysplasia-Poland), we evaluated 232 patients with FMD lesions confirmed in at least one vascular bed, out of 343 patients included in the registry. All patients underwent a detailed clinical evaluation including computed tomography angiography of intracranial and cervical arteries, as well as computed tomography angiography of the abdominal aorta, its branches, and upper and lower extremity arteries. In the study group, FMD lesions were most frequently found in renal arteries (87.5%). FMD was also found in cerebrovascular (24.6%), mesenteric (13.8%), and upper (3.0%) and lower extremity (9.9 %) arteries. Newly diagnosed FMD lesions were found in 34.1% of the patients, and previously undetected vascular complications were found in 25% of the patients. Among all F...Continue Reading

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Citations

Jul 9, 2020·Hypertension·Marco PappaccogliUNKNOWN European/International Fibromuscular Dysplasia Registry and Initiative (FEIRI) and the Working Group “Hypertension and the K
Apr 9, 2021·BMJ Case Reports·Demi Jordan WoodsAdnan Z Choudhury
Mar 20, 2021·Cardiovascular Research·Alexandre PersuAndrzej Januszewicz
Jun 11, 2021·Circulation Research·Esther S H KimSanthi K Ganesh
Jun 19, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Zubin J Modi, David B Kershaw

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Methods Mentioned

BETA
dissection
dissections

Software Mentioned

PASW Statistics
SPSS
ARCADIA
POL

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