Apr 1, 2020

Systematic Chemogenetic Library Assembly

BioRxiv : the Preprint Server for Biology
Stephen M Canham

Abstract

The assembly of chemogenetic libraries composed of chemical probes provides tremendous value to biomedical research, but requires substantial effort to ensure diversity as well as quality of the contents. We are assembling a chemogenetic library by data mining and crowdsourcing institutional expertise. We are sharing our methodology, lessons learned, and disclosing our current collection of 4186 compounds with their primary annotated gene targets.

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Mentioned in this Paper

Size
Sustain
Site
Microbial
Structure
Simulation
Dormancy
Mutation Abnormality
Population Group

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