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Systematic discovery and classification of human cell line essential genes

bioRxiv

Feb 18, 2015

Traver HartJason Moffat

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Abstract

The study of gene essentiality in human cells is crucial for elucidating gene function and holds great potential for finding therapeutic targets for diseases such as cancer. Technological advances in genome editing using clustered regularly interspaced short palindromic repeats (CRISPR)...read more

Mentioned in this Paper

Landscapes
Nuclear Proteins
Complex (molecular entity)
Human Cell Line
Study
Genome
RNA
Classification
Reverse Genetics
Genes, Essential
44
3
47
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  • Systematic discovery and classification of human cell line essential genes

    bioRxiv

    Feb 18, 2015

    Traver HartJason Moffat

    PMID: 990015412

    DOI: 10.1101/015412

    Abstract

    The study of gene essentiality in human cells is crucial for elucidating gene function and holds great potential for finding therapeutic targets for diseases such as cancer. Technological advances in genome editing using clustered regularly interspaced short palindromic repeats (CRISPR)...read more

    Mentioned in this Paper

    Landscapes
    Nuclear Proteins
    Complex (molecular entity)
    Human Cell Line
    Study
    44
    3
    47

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