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Systematic identification of cancer driving signaling pathways based on mutual exclusivity of genomic alterations

bioRxiv

Oct 2, 2014

OZGUN BABUREmek Demir

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Abstract

Recent cancer genome studies have identified numerous genomic alterations in cancer genomes. It is hypothesized that only a fraction of these genomic alterations drive the progression of cancer -- often called driver mutations. Current sample sizes for cancer studies, often in the hundr...read more

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Gene Mutation
Study
Scanning
Genome
Biochemical Pathway
Signal Pathways
Patterns
Biological Neural Networks
Signal Transduction
Disease Progression
9
15
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  • Systematic identification of cancer driving signaling pathways based on mutual exclusivity of genomic alterations

    bioRxiv

    Oct 2, 2014

    OZGUN BABUREmek Demir

    PMID: 990009878

    DOI: 10.1101/009878

    Abstract

    Recent cancer genome studies have identified numerous genomic alterations in cancer genomes. It is hypothesized that only a fraction of these genomic alterations drive the progression of cancer -- often called driver mutations. Current sample sizes for cancer studies, often in the hundr...read more

    Mentioned in this Paper

    Gene Mutation
    Study
    Scanning
    Genome
    Biochemical Pathway
    9
    15

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