Systematic Literature Review on Burden of Clostridioides difficile Infection in India.

Clinical Pathology
Canna J GhiaGautam S Rambhad

Abstract

Owing to limited diagnostic facilities and surveillance protocols, there is a paucity on the prevalence data of Clostridioides difficile infections (CDIs) in developing countries such as India. The aims of these studies are (1) to determine the prevalence of CDI in India, (2) to understand the risk factors of CDI, and (3) to determine the impact of different diagnostic methods on reported CDI rates. A systematic literature search was conducted using PubMed and Google Scholar database to identify Indian studies reporting the prevalence of CDI. A total of 31 studies, published between 1990 and 2020 were included in the final analysis. A chi-square test was used to determine statistically significant association between prevalence rates, accuracy of different diagnosis methods, and antibiotic usage rates of CDI. The prevalence of CDI was in the range of 3.4% to 18%, and the difference between regional prevalence of CDI was statistically significant (P < .001). The use of antibiotics, hospital stay, comorbidities, recent surgery, and the use of proton-pump inhibitors was considered as risk factors for the development of CDI. Compared to other regions, the rate of antibiotic usage was significantly higher in North India (P < .001). ...Continue Reading

References

Mar 9, 1978·The New England Journal of Medicine·J G BartlettA B Onderdonk
Sep 1, 1982·Pediatric Infectious Disease·D A BoenningR W Quinlan
Feb 5, 2000·The Journal of Hospital Infection·B DhawanN Sharma
May 15, 2003·The Journal of Antimicrobial Chemotherapy·Claudia ThomasThomas V Riley
Feb 16, 2006·Cleveland Clinic Journal of Medicine·Rebecca H Sunenshine, L Clifford McDonald
Feb 7, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John G Bartlett, Dale N Gerding
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Nov 26, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M J T CrobachE J Kuijper
Feb 16, 2010·The Journal of Hospital Infection·S S GhantojiK W Garey
Aug 11, 2010·The American Journal of the Medical Sciences·Latisha Heinlen, Jimmy D Ballard
Nov 19, 2010·Lancet·Martijn P BauerUNKNOWN ECDIS Study Group
May 10, 2011·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Meghraj IngleRanjit Mankeshwar
Mar 2, 2012·Emerging Infectious Diseases·Ghinwa DumyatiBrandi Limbago
Feb 15, 2013·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Venkatakrishnan H IyerBalakrishnan S Ramakrishna
Mar 13, 2013·Antimicrobial Agents and Chemotherapy·Kevin A BrownDavid N Fisman
Mar 26, 2013·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Meghraj IngleCamilla Rodrigues
Apr 27, 2013·The Journal of Antimicrobial Chemotherapy·Abhishek DeshpandeCurtis J Donskey
Sep 26, 2013·Journal of Pharmacy Practice·Daryl D Depestel, David M Aronoff
Dec 11, 2013·The Journal of Antimicrobial Chemotherapy·Claudia Slimings, Thomas V Riley
Jan 31, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Luis Furuya-KanamoriArchie C Clements
Mar 12, 2016·Balkan Medical Journal·Özlem YoldaşRecep Keşli
Jun 21, 2017·Indian Journal of Pathology & Microbiology·Lavanya SegarK S Seetha
Oct 27, 2017·The Indian Journal of Medical Research·Meenakshi SinghSafrun Mahmood
Jan 7, 2018·Journal of Clinical Microbiology·G A RoldanN R Pollock
Feb 21, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L Clifford McDonaldMark H Wilcox
Nov 16, 2018·Indian Journal of Medical Microbiology·Tanu SinghalPooja Thakkar
Jan 20, 2019·Infectious Diseases and Therapy·Daniel CurcioJorge Correa
Apr 4, 2020·The New England Journal of Medicine·Alice Y GuhUNKNOWN Emerging Infections Program Clostridioides difficile Infection Working Group

❮ Previous
Next ❯

Software Mentioned

Google Scholar
Excel

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.