Systematic review: faecal transplantation for the treatment of Clostridium difficile-associated disease

Alimentary Pharmacology & Therapeutics
B GuoL A Dieleman

Abstract

Management of recurrent Clostridium difficile-associated disease (CDAD), particularly in elderly patients, remains clinically challenging. Faecal transplantation (FT) may restore normal microbiota and break the cycle of recurrent CDAD. To critically appraise the clinical research evidence on the safety and effectiveness of FT compared with standard care in the treatment of patients with CDAD. A comprehensive literature search was conducted by a research librarian to identify relevant studies published between 2000 and 2011. The Cochrane Library, PubMed, EMBASE, CINAHL, Biological Abstracts, BIOSIS Previews and Web of Science were searched using the following Medical Subject Headings (MeSH) terms and keywords, alone or in combination: Clostridium infections/Clostridium difficile/pseudomembranous/colitis/faeces/rectal/colon flora/gastrointestinal/nasogastric tube/enema/donor/transplant/infusion/bacteriotherapy/human probiotic infusion. Methodological quality of the included case series studies was assessed in terms of patient selection criteria, consecutive recruitment, prospective data collection, reporting of lost to follow-up, and follow-up rates. No controlled studies were found. Based on the weak evidence from seven full-tex...Continue Reading

References

Mar 1, 1997·Annals of Internal Medicine·D J CookR B Haynes
Jul 1, 1998·Clinical Obstetrics and Gynecology·J F Peipert, M G Phipps
Feb 21, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Johannes AasJohan S Bakken
Jun 29, 2004·Journal of Clinical Gastroenterology·Thomas J BorodySteven Siarakas
Jul 9, 2004·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Susan M Poutanen, Andrew E Simor
May 7, 2005·American Journal of Infection Control·Linda McKibbenUNKNOWN Heathcare Infection Control Practices Advisory Committee
Jul 16, 2005·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Linda McKibbenUNKNOWN Healthcare Infection Control Practices Advisory Committee
Sep 24, 2005·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Jacques PépinBenoit Cossette
Nov 3, 2005·Nature Clinical Practice. Gastroenterology & Hepatology·Christina M Surawicz
Nov 23, 2006·Annals of Internal Medicine·John G Bartlett
Mar 21, 2007·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Joseph F RodemannChristian D Stone
May 8, 2007·American Journal of Infection Control·Lynne V McFarlandGregory J Raugi
Feb 7, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Robert C OwensCarlene A Muto
Feb 7, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John G Bartlett
May 31, 2008·Current Infectious Disease Reports·Bayan MissaghiRobert C Owens
Oct 31, 2008·The New England Journal of Medicine·Ciarán P Kelly, J Thomas LaMont
Jan 28, 2009·American Journal of Infection Control·Denise GravelUNKNOWN Canadian Nosocomial Infection Surveillance Program
Jul 18, 2009·International Journal of Antimicrobial Agents·Martijn P Bauer, Jaap T van Dissel
Apr 3, 2009·World Journal of Gastroenterology : WJG·Perry Hookman, Jamie S Barkin
Apr 9, 2009·Postgraduate Medical Journal·T MonaghanY R Mahida
May 22, 2009·Gastroenterology·Daniel A Leffler, J Thomas Lamont
Jun 23, 2009·Disease-a-month : DM·Robin B McFee, George G Abdelsayed
Jul 30, 2009·Transplant Infectious Disease : an Official Journal of the Transplantation Society·J M PogueD G Frame
Sep 4, 2009·QJM : Monthly Journal of the Association of Physicians·A A MacConnachieR A Seaton
Nov 26, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M P BauerUNKNOWN European Society of Clinical Microbiology and Infectious Diseases
Feb 2, 2010·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Michael S SilvermanDylan R Pillai
May 21, 2010·Journal of Clinical Gastroenterology·Faith RohlkeNeil Stollman
Jul 29, 2010·Scandinavian Journal of Infectious Diseases·Kjetil GarborgAnders Sundøy
Dec 24, 2010·Annals of the New York Academy of Sciences·John G Bartlett
Jan 5, 2011·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Takayuki YamamotoKoichi Matsumoto
Apr 20, 2011·Nature Reviews. Gastroenterology & Hepatology·Christina M Surawicz, Jacob Alexander
May 11, 2011·Journal of Clinical Gastroenterology·Liam Martin
May 17, 2011·Drugs·Claire M F van Nispen tot PannerdenErnst J Kuipers
Jun 21, 2011·Alimentary Pharmacology & Therapeutics·J LandyA L Hart
Jul 1, 2011·Journal of Clinical Gastroenterology·Lawrence J BrandtJordana Campbell
Jul 20, 2011·Surgical Infections·Christine S Cocanour
Jul 7, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas J LouieWalter Krulicki

❮ Previous
Next ❯

Citations

Sep 4, 2012·Current Gastroenterology Reports·Fergus Shanahan
May 10, 2013·Current HIV/AIDS Reports·Paul J ColliniDavid H Dockrell
Apr 4, 2013·Current Infectious Disease Reports·Nuntra Suwantarat, David A Bobak
Sep 5, 2012·Nature Reviews. Gastroenterology & Hepatology·Harry J FlintSylvia H Duncan
Apr 30, 2013·Inflammatory Bowel Diseases·Stacy A KahnDavid T Rubin
Dec 12, 2012·Archives of Disease in Childhood. Fetal and Neonatal Edition·Kathleen SimJohn Simon Kroll
Nov 16, 2012·Therapeutic Advances in Gastroenterology·Faith Rohlke, Neil Stollman
Nov 28, 2012·Antimicrobial Resistance and Infection Control·Jean Carlet
Aug 8, 2013·World Journal of Gastroenterology : WJG·Dinesh VyasArpita Vyas
Jan 25, 2013·Clinical Medicine : Journal of the Royal College of Physicians of London·Neerav M JoshiDavid S Rampton
Aug 13, 2013·The British Journal of Nutrition·Susan E PowerGerald F Fitzgerald
Aug 24, 2012·Future Microbiology·Michelle D CairnsBrendan W Wren
May 9, 2014·PharmacoEconomics·Kari A MergenhagenJoseph A Paladino
Dec 3, 2014·The Surgical Clinics of North America·Jason A Luciano, Brian S Zuckerbraun
May 7, 2013·Gastrointestinal Endoscopy·Lawrence J Brandt, Olga C Aroniadis
Feb 1, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M TvedeM Helms
Nov 5, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R U VarierR E Nelson
Oct 3, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·N KapelF Joly
Oct 3, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R SinghS E Geerlings
May 23, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R SinghF J Bemelman
Jul 26, 2012·Alimentary Pharmacology & Therapeutics·J L AndersonK Whelan
Oct 26, 2012·Alimentary Pharmacology & Therapeutics·E MattilaV-J Anttila
Apr 19, 2013·Microbial Biotechnology·Pieter Van den AbbeeleTom Van de Wiele
Sep 19, 2014·Journal of Veterinary Internal Medicine·A SchosterL Guardabassi
Nov 28, 2013·Environmental Microbiology·Karen De RoyNico Boon
Jan 1, 2014·International Journal of Clinical Practice·M Dodin, D E Katz
Feb 18, 2015·Clinical Journal of Oncology Nursing·Lisa M BlackburnHaley Kreider
Dec 22, 2012·Beneficial Microbes·E O PetrofE Allen-Vercoe
Mar 19, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Raghu U VarierRichard E Nelson
Jan 9, 2015·Current Treatment Options in Gastroenterology·Christina M Surawicz
Jan 13, 2015·Annales pharmaceutiques françaises·F BarbutP Bourlioux
Oct 15, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S B DebastUNKNOWN European Society of Clinical Microbiology and Infectious Diseases
May 18, 2016·Critical Care : the Official Journal of the Critical Care Forum·Jean-Louis VincentMassimo Antonelli
Aug 3, 2016·Alimentary Pharmacology & Therapeutics·Sahil KhannaPurna Kashyap
Aug 17, 2016·PloS One·Sinan WangBangmao Wang
Dec 25, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Susy S HotaSusan M Poutanen
May 3, 2016·Therapeutic Advances in Gastroenterology·William M TauxeColleen S Kraft
Feb 21, 2018·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·L Clifford McDonaldMark H Wilcox

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacteriotherapy (ASM)

Bacteriotherapy, also known as fecal transplantation, involves the transfer of stool from a healthy donor into the gastrointestinal tract for the purpose of treating recurrent C. difficile colitis. Here is the latest on bacteriotherapy.

Bacteriotherapy

Bacteriotherapy, also known as fecal transplantation, involves the transfer of stool from a healthy donor into the gastrointestinal tract for the purpose of treating recurrent C. difficile colitis. Here is the latest on bacteriotherapy.

Related Papers

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Ethan GoughAmee R Manges
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Johan S BakkenFecal Microbiota Transplantation Workgroup
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Jonathan S ZipurskyKathryn B Kirkland
© 2022 Meta ULC. All rights reserved