Systematic Review of Kingella kingae Musculoskeletal Infection in Children: Epidemiology, Impact and Management Strategies

Pediatric Health, Medicine and Therapeutics
Maria WongCelia Cooper

Abstract

Kingella kingae, a pathogen often responsible for musculoskeletal infections in children is the most common cause of septic arthritis and osteomyelitis in children 6 to 36 months of age. The aim of this study was to perform a systematic review of previous studies to determine the proportion of K. kingae in bacteriologically proven musculoskeletal infections among the pediatric population. A secondary objective was to describe the diagnostic strategies and outcome of patients with musculoskeletal infections caused by K. kingae. A systematic review was conducted to identify publications that report on musculoskeletal infections caused by K. kingae in the pediatric population (patients 0 to <18 years old with microbiologic culture and/or polymerase chain reaction (PCR) confirmation of K. kingae and a description of the musculoskeletal infection involved). Of 144 studies included in this review, we sought to determine the proportion of K. kingae pediatric musculoskeletal infections. A total of 711 (30.8%) out of 2308 pediatric cases with culture and/or PCR proven musculoskeletal infections had K. kingae successfully identified from twenty-nine studies. Of the 1070 patients who were aged less than 48 months, K. kingae was the organi...Continue Reading

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Citations

Jan 20, 2021·Journal of Paediatrics and Child Health·Khalfan Al AbdaliPamela Palasanthiran
Jan 9, 2021·Enfermedades infecciosas y microbiología clínica·Borja Guarch-IbáñezPilar Villalobos
Mar 2, 2021·The Bone & Joint Journal·Benoit CoulinDimitri Ceroni
Jul 22, 2021·BMC Infectious Diseases·Kaoutar MoutaouakkilMoulay Abderrahmane Afifi
Jul 15, 2021·Journal of Paediatrics and Child Health·Pablo Yagupsky
Aug 7, 2021·Enfermedades Infecciosas Y Microbiologia Clinica·Alicia SerreraFernando Cabañas
Nov 5, 2020·Enfermedades infecciosas y microbiología clínica·Alicia SerreraFernando Cabañas
Aug 14, 2021·Expert Review of Anti-infective Therapy·Alex Van BelkumChristine C Ginocchio

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Ovid Medline
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