Systematic review of ototoxic pre-surgical antiseptic preparations - what is the evidence?

Journal of Otolaryngology - Head & Neck Surgery = Le Journal D'oto-rhino-laryngologie Et De Chirurgie Cervico-faciale
Shubhi Singh, Brian Blakley

Abstract

There is uncertainty regarding the safety of surgical antiseptic preparations in the ear. A systematic review of the literature was conducted to assess the evidence regarding ototoxicity of surgical antiseptic preparations. A literature search was conducted using the PRISMA methods. Key words included "ototoxicity" "hearing loss", "antiseptic", "surgical preparation", "tympanoplasty", "vestibular dysfunction", "chlorhexidine", "iodine", "povidone", "ethanol", and "hydrogen peroxide" using Medline, Embase, Cochrane Library, Scopus and Web of Science. We included peer-reviewed papers that 1) objectively measured ototoxicity in humans or animals through hearing, vestibular function or histologic examination, 2) studied topically applied surgical antiseptic preparations, 3) were either in English or had an English abstract. We excluded papers that were 1) in vitro studies, 2) ear trauma studies, 3) studies of ototoxic ear drops intended for therapy, or 4) case reports. Studies included in the final review were screened using the PRISMA method. Current systematic review registration number pending: 83,675. Fifty-six papers were identified as using PRISMA criteria. After applying our exclusion criteria, 13 papers met overall study cr...Continue Reading

References

Jan 1, 1985·Archives of Oto-rhino-laryngology·Y Igarashi, J Suzuki
Nov 1, 1966·The Journal of Laryngology and Otology·S Rauch
Sep 1, 1971·The Journal of Laryngology and Otology·P G Bicknell
Oct 1, 1983·Archives of Otolaryngology·T Morizono, M A Sikora
Mar 1, 1982·Acta Oto-laryngologica·J Aursnes
Apr 1, 1982·Archives of Otolaryngology·T Morizono, M A Sikora
Jul 1, 1981·Acta Oto-laryngologica·T Morizono, M A Sikora
Sep 1, 1981·Acta Oto-laryngologica·J Aursnes
Oct 17, 2003·The Journal of Laryngology and Otology·Recep YagizAhmet Rifat Karasalihoglu
Nov 7, 2003·The Laryngoscope·Ronen PerezHaim Sohmer
Feb 6, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Marc-Elie NaderSam Joseph Daniel
Jul 12, 2011·International Journal of Pediatric Otorhinolaryngology·T IchibangaseT Morizono
Jan 16, 2014·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Mahmut OzkirişLevent Saydam
Jul 12, 2016·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kenneth D Steinsapir, Julie A Woodward

❮ Previous
Next ❯

Citations

Nov 26, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Westley S MoriIan A Maher
Jun 23, 2020·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Andries Francois van StratenAndrew Whitelaw
Jan 2, 2019·Laryngoscope Investigative Otolaryngology·Nicklas C OrobelloPatrick J Antonelli
Oct 21, 2020·Pharmacotherapy·Habib G RizkWendy M Bullington
Jun 22, 2021·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Peter L Santa MariaLaurent A Bekale
Sep 18, 2021·Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale·Behrouz BaratiGhazal Norouzi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Related Papers

Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Luís Carlos Lopes-JúniorRegina Aparecida Garcia de Lima
The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Huaping HuangMei He
© 2022 Meta ULC. All rights reserved