Systematic review of pineal cysts surgery in pediatric patients.

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Joham Choque-VelasquezJuha Hernesniemi

Abstract

We present a consecutive case series and a systematic review of surgically treated pediatric PCs. We hypothesized that the symptomatic PC is a progressive disease with hydrocephalus at its last stage. We also propose that PC microsurgery is associated with better postoperative outcomes compared to other treatments. The systematic review was conducted in PubMed and Scopus. No clinical study on pediatric PC patients was available. We performed a comprehensive evaluation of the available individual patient data of 43 (22 case reports and 21 observational series) articles. The review included 109 patients (72% females). Ten-year-old or younger patients harbored smaller PC sizes compared to older patients (p < 0.01). The pediatric PCs operated on appeared to represent a progressive disease, which started with unspecific symptoms with a mean cyst diameter of 14.5 mm, and progressed to visual impairment with a mean cyst diameter of 17.8 mm, and hydrocephalus with a mean cyst diameter of 23.5 mm in the final stages of disease (p < 0.001). Additionally, 96% of patients saw an improvement in their symptoms or became asymptomatic after surgery. PC microsurgery linked with superior gross total resection compared to endoscopic and stereotac...Continue Reading

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Citations

Apr 4, 2021·Cancers·Gaia FaveroRita Rezzani
May 28, 2021·Practical Neurology·Michael D JenkinsonThomas Santarius

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Methods Mentioned

BETA
surgical resection

Software Mentioned

Scopus
PROSPERO
PubMed

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