Systematic reviews identify important methodological flaws in stroke rehabilitation therapy primary studies: review of reviews

Journal of Clinical Epidemiology
Pasqualina SantaguidaParminder Raina

Abstract

A "review of reviews" was undertaken to assess methodological issues in studies evaluating nondrug rehabilitation interventions in stroke patients. MEDLINE, CINAHL, PsycINFO, and the Cochrane Database of Systematic Reviews were searched from January 2000 to January 2008 within the stroke rehabilitation setting. Electronic searches were supplemented by reviews of reference lists and citations identified by experts. Eligible studies were systematic reviews; excluded citations were narrative reviews or reviews of reviews. Review characteristics and criteria for assessing methodological quality of primary studies within them were extracted. The search yielded 949 English-language citations. We included a final set of 38 systematic reviews. Cochrane reviews, which have a standardized methodology, were generally of higher methodological quality than non-Cochrane reviews. Most systematic reviews used standardized quality assessment criteria for primary studies, but not all were comprehensive. Reviews showed that primary studies had problems with randomization, allocation concealment, and blinding. Baseline comparability, adverse events, and co-intervention or contamination were not consistently assessed. Blinding of patients and provi...Continue Reading

References

Jan 1, 1991·Journal of Clinical Epidemiology·A D OxmanD L Streiner
Jan 1, 1991·Journal of Clinical Epidemiology·A D Oxman, G H Guyatt
Sep 15, 2000·BMJ : British Medical Journal·M CampbellP Tyrer
Apr 15, 2004·Plastic and Reconstructive Surgery·Achilleas ThomaEric Duku
Jul 13, 2004·Journal of Clinical Epidemiology·Isabelle BoutronPhilippe Ravaud
Jul 15, 2004·Journal of Epidemiology and Community Health·Miguel Delgado-Rodríguez, Javier Llorca
Dec 3, 2005·The Australian Journal of Physiotherapy·Sharon Hakkennes, Jennifer L Keating
Dec 24, 2005·Archives of Physical Medicine and Rehabilitation·Susan D HornJeffrey Teraoka
Feb 16, 2006·Journal of the Neurological Sciences·Kim C StewartJeffery J Summers
Mar 22, 2006·Journal of Rehabilitation Medicine·Roland P S Van PeppenGert Kwakkel
May 30, 2006·Archives of Physical Medicine and Rehabilitation·Susy M BraunDerick T Wade
May 30, 2006·Archives of Physical Medicine and Rehabilitation·Shawn M RobbinsJanet L Brown
Jul 19, 2006·Journal of Rehabilitation Research and Development·Gerdienke B PrangeMaarten J Ijzerman
Sep 21, 2006·International Journal of Technology Assessment in Health Care·Torben LarsenJan Sorensen
Nov 30, 2006·The Australian Journal of Physiotherapy·Louise AdaColleen G Canning
Apr 28, 2007·Stroke; a Journal of Cerebral Circulation·Pamela SeenanPeter Langhorne
Jul 12, 2007·Occupational Therapy International·Marjorie L UrtonMegan R Neill
Aug 19, 2007·Topics in Stroke Rehabilitation·Holly LyntonSamuel Shiflett
Oct 19, 2007·PLoS Medicine·Jan P VandenbrouckeUNKNOWN STROBE Initiative
Feb 20, 2008·Annals of Internal Medicine·Isabelle BoutronUNKNOWN CONSORT Group
Feb 20, 2008·Annals of Internal Medicine·Isabelle BoutronUNKNOWN CONSORT Group
May 21, 2008·Annals of Internal Medicine·Evelyn P WhitlockKaren A Robinson
Nov 18, 2008·Journal of Clinical Epidemiology·Matthew E FalagasEleni Ioannidou
Dec 17, 2008·Journal of Clinical Epidemiology·Norine C FoleyMark Speechley
Dec 17, 2008·Circulation·Donald Lloyd-JonesUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Mar 14, 2009·Journal of Clinical Epidemiology·Anne M MoseleyCatherine Sherrington
Jul 18, 2009·Lancet Neurology·Peter LanghorneAlex Pollock
Jan 1, 2006·Occupational Therapy in Health Care·Anna Bjorklund, Ashley Fecht

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Citations

Feb 21, 2013·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Are Brean
Mar 27, 2015·Journal of Clinical Periodontology·Clovis Mariano FaggionMarco Antonio Alarcón
Jul 20, 2017·Systematic Reviews·Kusala PussegodaDavid Moher
Sep 15, 2017·Chinese Journal of Integrative Medicine·Xin-Lin ChenXian-Tao Li

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