Systematic study on factors influencing the performance of interdetector scatter recovery in small-animal PET

Medical Physics
Seungeun LeeJae Sung Lee

Abstract

Interdetector scatter (IDS) is a triple coincidence caused by the Compton scatter of an annihilation photon from one detector block to another which frequently occurs in small-animal positron emission tomography (PET). By finding the true lines-of-response (LORs) of annihilation photon pairs among three possible LORs in IDS events, we can utilize these recovered events to improve the sensitivity of PET systems. IDS recovery should be accurate to yield reliable images with relatively short scan times. We systemically investigated physical factors affecting IDS recovery performance, focusing on the reconstructed image quality of small-animal PET. We evaluated sensitivity increase, recovery accuracy, and image quality by applying different combinations of energy window, recovery scheme, and scanner properties. We used GATE Monte Carlo simulation to acquire coincidence events from a NEMA NU 4-2008 image quality phantom using small-animal PET scanner with axial field of view of 55 mm and diameter of 64 mm. We first defined energy window criteria to obtain valid IDS events. Their role was to assign triple coincidences as IDS events and to restrict the number of LOR candidates to two. We tested three different energy windows around 51...Continue Reading

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Citations

Jun 24, 2020·Physics in Medicine and Biology·Seungeun LeeJae Sung Lee
May 6, 2019·Physics in Medicine and Biology·Guen Bae Ko, Jae Sung Lee
Jul 24, 2020·Physics in Medicine and Biology·Haewook Park, Jae Sung Lee
Aug 27, 2021·Physics in Medicine and Biology·Seungeun Lee, Jae Sung Lee

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