PMID: 11342920May 9, 2001Paper

Systematic transperineal ultrasound guided template biopsy of the prostate in patients at high risk

The Journal of Urology
Todd C IgelR O Parra

Abstract

A negative biopsy result does not necessarily equate with cancer in specific high risk groups. We describe an alternative systematic biopsy technique for evaluating this subgroup of patients. From March 1997 to May 1999 a total of 88 men underwent systematic ultrasound guided biopsy using the transperineal template technique. All patients had undergone at least 1 and 75 (85%) had undergone 2 or more previous sets of biopsies. In addition, study inclusion required high risk parameters, including prostate specific antigen (PSA) velocity greater than 0.75 ng./ml., PSA greater than 10 ng./ml. or previous prostatic intraepithelial neoplasia on biopsy, and/or atypical small cell acinar proliferation. Cancer was identified in 38 of the 88 men (43%) in this high risk subgroup undergoing repeat biopsy. A mean of 15.1 previous biopsy cores had been obtained. The most common biopsy grade was 6 (range 4 to 9). Adenocarcinoma was identified in the transition zone area in 29 of 38 cases (76%), including 15 (39%) in which disease was detected in the transition zone only. Persistent PSA acceleration greater than 0.75 ng./ml. was the major indicator for transperineal template biopsy in 83 of the 88 patients (94%). The only significant independe...Continue Reading

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Citations

Apr 20, 2006·International Journal of Clinical Oncology·Satoru KawakamiKazunori Kihara
Apr 18, 2009·Current Urology Reports·Martha K Terris
Jul 15, 2003·Urologic Oncology·Joseph C Presti
Jul 15, 2003·Urologic Oncology·Maxwell V MengGary D Grossfeld
Sep 8, 2007·Nature Clinical Practice. Urology·Joseph C Presti
Aug 23, 2012·Nature Reviews. Clinical Oncology·Olivier RouvièreJean-Yves Chapelon
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Apr 13, 2010·Journal of Endourology·Samir S Taneja, Malcolm Mason
Apr 7, 2010·Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada·Assaad El-Hakim, Sabri Moussa
Nov 24, 2011·Prostate Cancer·J L Dominguez-EscrigD Greene
Apr 16, 2014·BJU International·Hideki TakeshitaKazunori Kihara
Sep 5, 2013·International Journal of Urology : Official Journal of the Japanese Urological Association·Ashley J RidoutCaroline M Moore
Jan 4, 2012·Histopathology·David G Bostwick, Liang Cheng
Aug 8, 2007·International Journal of Urology : Official Journal of the Japanese Urological Association·Satoru KawakamiIwao Fukui
Oct 3, 2009·International Journal of Urology : Official Journal of the Japanese Urological Association·Masahito SuzukiKazunori Kihara
Mar 15, 2014·Current Opinion in Urology·Niccolò M Passoni, Thomas J Polascik
Feb 1, 2013·Current Urology·Christopher M BredeStephen Jones
Aug 3, 2004·International Journal of Urology : Official Journal of the Japanese Urological Association·Satoru KawakamiYukio Kageyama
Aug 27, 2004·BJU International·Steven P Petrou, Todd C Igel
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Jan 24, 2004·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·David G Bostwick, Junqi Qian

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