PMID: 9425739Jan 13, 1998Paper

Systemic antigen in the treatment of T-cell-mediated autoimmune diseases

Immunology Today
R LiblauH O McDevitt

Abstract

Systemic injection of antigen is one of the approaches that reproducibly induces effective antigen-specific hyporesponsiveness. Here, Roland Liblau and colleagues discuss the cellular and molecular bases of such tolerance, review the current use of this therapeutic strategy in experimental organ-specific autoimmune diseases and analyse what steps are necessary to make this approach suitable for clinical use.

References

Dec 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·S D SharmaS Sriram
Mar 8, 1991·Science·B Rocha, H von Boehmer
Jul 1, 1995·The Journal of Experimental Medicine·P AicheleH Pircher
Oct 1, 1993·International Immunology·C MamalakiD Kioussis
Feb 1, 1993·The Journal of Experimental Medicine·H J Burstein, A K Abbas
May 1, 1993·The Journal of Experimental Medicine·B RochaH Von Boehmer
Jan 1, 1996·European Journal of Immunology·D FalbT Kamradt
Nov 1, 1995·Journal of the Neurological Sciences·K G Warren, I Catz
Mar 22, 1996·Science·T ForsthuberP V Lehmann
Apr 2, 1996·Proceedings of the National Academy of Sciences of the United States of America·R S LiblauH O McDevitt
Jun 14, 1996·Cell·A Fraser, G Evan
Mar 1, 1955·The Journal of Experimental Medicine·F J DIXON, P H MAUER
Dec 15, 1964·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·N A MITCHISON

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Citations

Mar 15, 2000·Muscle & Nerve·J M Lindstrom
Oct 12, 2000·Diabetes/metabolism Research and Reviews·K N Potter, T J Wilkin
Dec 4, 1998·Springer Seminars in Immunopathology·A P Cope, G Sønderstrup
Dec 5, 2000·Current Opinion in Immunology·L C Harrison, D A Hafler
Apr 23, 2003·Clinical Immunology : the Official Journal of the Clinical Immunology Society·M SchmiedD A Hafler
Jun 3, 2004·Nature Reviews. Immunology·Lloyd Mayer, Ling Shao
Jul 6, 2001·Scandinavian Journal of Immunology·F Monneaux, S Muller
Jul 6, 2001·Scandinavian Journal of Immunology·J F Bach
Jul 23, 2003·Journal of Thrombosis and Haemostasis : JTH·R GreenwoodJ A Frelinger
May 23, 2007·Proceedings of the National Academy of Sciences of the United States of America·Eliane PiaggioRoland S Liblau
Nov 15, 2007·Proceedings of the National Academy of Sciences of the United States of America·F OdoardiA Flügel
Jun 26, 2002·Proceedings of the National Academy of Sciences of the United States of America·Felix J BakerMark M Davis
Oct 31, 1998·Immunological Reviews·G Sønderstrup, H McDevitt
May 3, 2003·The Journal of Clinical Investigation·Nathan R MartinezLeonard C Harrison
Jul 20, 1999·The Journal of Clinical Investigation·B CoonM G von Herrath
Jul 27, 2010·Journal of Autoimmunity·Fumi MiyagawaStephen I Katz
Jul 4, 2007·Revue neurologique·R GoldA Chan
May 4, 2010·Annals of Neurology·Jie LuoJon M Lindstrom
Mar 14, 2002·International Reviews of Immunology·K L LeggeH Zaghouani
Jun 14, 2016·Journal of Immunology Research·Larissa Lumi Watanabe IshikawaAlexandrina Sartori
Mar 3, 2004·Annals of Neurology·Leslie P WeinerMinnie McMillan
Sep 28, 1999·Current Opinion in Neurology·J H NoseworthyH P Hartung
Sep 2, 1998·Current Opinion in Neurology·R S Liblau, B Fontaine
Sep 24, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Amy D HigginsAdam J Adler
Jan 7, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Agnès Hartemann-HeurtierRoland S Liblau
Oct 25, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·S NagataT T MacDonald
Jun 13, 2000·Journal of Neuropathology and Experimental Neurology·D Annesley-WilliamsF M Brett
Jun 22, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·D J WeaverR Tisch
Aug 24, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Lolita ZaliauskieneJames F Collawn
Apr 29, 1999·Brain Pathology·R GoldH P Hartung

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