PMID: 6981753Jul 24, 1982Paper

Systemic Haemophilus influenzae infection in childhood

The Medical Journal of Australia
W KooP Tomlinson

Abstract

Forty-nine children who had systemic Haemophilus infection and were treated at the Westmead Centre, Sydney, over a two-year period are described. The majority (29 of 49 children) were aged two years or less. Epiglottis and meningitis accounted for 77% of these infections. All H. influenzae isolates associated with clinical disease were of the capsular type b. Eight per cent (four of 50) of H. influenzae infections were caused by beta-lactamase producing strains. There was no geographic clustering or seasonal variation. There was no mortality. Major morbidity included two patients who had epiglottis and required tracheostomy, and two patients who had meningitis developed bilateral profound sensorineural deafness. No secondary cases were detected in household contacts of 21 patients with H. influenzae meningitis during the study period. Epiglottis frequently occurs in very young children. The rapid response to antibiotic treatment suggests that early cases of epiglottis may be undiagnosed, but treated with antibiotic agents in the community.

References

Jun 13, 1981·The Medical Journal of Australia·N HoskingW Newman
Dec 18, 1980·The New England Journal of Medicine·J P DavisM LaVenture
Nov 15, 1980·British Medical Journal·P Holt

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Citations

Feb 1, 1985·Australian and New Zealand Journal of Medicine·W W Koo
Jun 17, 1991·The Medical Journal of Australia·P B McIntyreL M Irwig
May 1, 1990·Archives of Disease in Childhood·B TrollforsK Strangert
Apr 1, 1984·Australian and New Zealand Journal of Medicine·P D SlyJ S Wagener
Sep 29, 1984·The Medical Journal of Australia·R Kemp

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