Systemic involvement in localized scleroderma/morphea

Clinics in Dermatology
Anna Gorkiewicz-Petkow, Agnieszka Kalinska-Bienias

Abstract

Localized scleroderma (LoSc), also known as morphea, is a rare fibrosing disorder of the skin and underlying tissues. Sclerosis is mainly limited to the skin, but subcutaneous tissue, fascia, and underlying muscles and bone may also be involved. In some cases, systemic manifestation with visceral abnormalities may occur. Several publications have focused on significant aspects of LoSc: genetics, immunity, epidemiology, scoring systems, and unification of classifications. Clinical studies featuring large cohorts with the disease published by various international study groups have been of great value in furthering the diagnostic and therapeutic management of LoSc.

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Citations

Sep 1, 2015·Clinics in Dermatology·Nikolai TsankovRazvigor Darlenski
Nov 23, 2017·Anais Brasileiros De Dermatologia·Anil Gulsel BahaliNahide Onsun
Sep 15, 2020·Journal of Wound Care·Georgeanne CornellJonathon Wilson
Apr 19, 2018·Dermatology Research and Practice·Giuggioli DiliaFerri Clodoveo
Aug 5, 2021·International Journal of Dermatology·Elena S Snarskaya, Kseniia D Vasileva

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