Systemic lidocaine to improve postoperative quality of recovery after ambulatory laparoscopic surgery

Anesthesia and Analgesia
Gildasio S De OliveiraRobert J McCarthy

Abstract

Perioperative systemic lidocaine has been shown to have beneficial postoperative analgesic effects. The only previous study examining the use of lidocaine in the outpatient setting did not detect an opioid-sparing effect after hospital discharge. More importantly, it is unknown whether systemic lidocaine provides a better postoperative quality of recovery to patients undergoing ambulatory surgery. Our objective in the current study was to examine the effect of systemic lidocaine on postoperative quality of recovery in patients undergoing outpatient laparoscopic surgery. The study was a prospective, randomized, double-blind, placebo-controlled clinical trial. Healthy female subjects were randomized to receive lidocaine (1.5 mg/kg bolus followed by a 2 mg/kg/h infusion until the end of the surgical procedure) or the same volume of saline. The primary outcome was the Quality of Recovery-40 questionnaire at 24 hours after surgery. A 10-point difference represents a clinically relevant improvement in quality of recovery based on previously reported values on the mean and range of the Quality of Recovery-40 score in patients after anesthesia and surgery. Other data collected included opioid consumption, pain scores, and time to meet ...Continue Reading

References

Mar 31, 2000·British Journal of Anaesthesia·P S MylesS Hensen
Feb 25, 2003·Anesthesia and Analgesia·Martin LuginbühlMichele Curatolo
May 11, 2007·Best Practice & Research. Clinical Anaesthesiology·Narinder Rawal
Jun 21, 2007·Anesthesia and Analgesia·Francisco J HerreraFrances Chung
Jun 29, 2010·British Journal of Anaesthesia·P W H PengF Chung
Nov 10, 2010·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Louise VigneaultDean A Fergusson
Jun 28, 2011·Lancet·Christopher L Wu, Srinivasa N Raja
Jul 28, 2011·Anesthesiology·Alparslan Turan, Daniel I Sessler

❮ Previous
Next ❯

Citations

Oct 8, 2013·Journal de gynécologie, obstétrique et biologie de la reproduction·J F Le BrunJ M Classe
Sep 22, 2012·Regional Anesthesia and Pain Medicine·Rachit OhriGary Strichartz
Jan 17, 2014·Obesity Surgery·Adrian AlvarezAshish C Sinha
Sep 30, 2014·Peptides·Richard J Bodnar
Mar 24, 2016·Journal of Natural Science, Biology, and Medicine·Seyed Gholam Ali JorsaraeiMasoumeh Golsorkhtabaramiri
Feb 13, 2014·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Shireen AhmadRobert J McCarthy
Sep 22, 2015·Frontiers in Surgery·Geoffrey P Dobson
Jun 6, 2015·World Journal of Surgery·Nicholas T VenthamKenneth C H Fearon
Apr 15, 2015·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Ramamani MariappanLashmi Venkatraghavan
Dec 17, 2014·Revista brasileira de anestesiologia·Tania Cursino de Menezes CouceiroMarcelo Moraes Valença
May 1, 2015·Brazilian Journal of Anesthesiology·Tania Cursino de Menezes CouceiroMarcelo Moraes Valença
Mar 18, 2015·Journal de gynécologie, obstétrique et biologie de la reproduction·L BruneauF-X Laurent
Oct 19, 2016·Clinical and Experimental Emergency Medicine·Brendan Michael Fitzpatrick, Michael Eugene Mullins
Jan 24, 2017·Anesthesiology·Lauren K Dunn, Marcel E Durieux
Apr 4, 2017·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Avi A Weinbroum
Aug 20, 2014·Anesthesia and Analgesia·Fabian O KooijMarkus W Hollmann
Feb 24, 2018·Current Opinion in Anaesthesiology·Allana MunroRonald B George
Jul 18, 2015·The Cochrane Database of Systematic Reviews·Peter KrankeStephanie Weibel
Jun 5, 2018·The Cochrane Database of Systematic Reviews·Stephanie WeibelPeter Kranke
Dec 30, 2017·Medwave·María Magdalena González, Fernando Altermatt
Oct 1, 2019·Current Opinion in Anaesthesiology·Philippe RichebéJulien Raft
Feb 20, 2016·Anesthesia and Analgesia·Jeffrey A Klein, Daniel R Jeske
Dec 9, 2014·The Clinical Journal of Pain·Gildasio S De OliveiraRobert J McCarthy

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Anesthesia and Analgesia
Armin SchubertMary D Peterson
Current Opinion in Anaesthesiology
Olivia Finnerty, John G McDonnell
© 2021 Meta ULC. All rights reserved