PMID: 11330557May 2, 2001Paper

Systemic lupus erythematosus and peritoneal dialysis: outcomes and infectious complications

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
J W HuangT J Tsai

Abstract

Systemic lupus erythematosus (SLE) is the most common secondary glomerulonephritis resulting in end-stage renal disease (ESRD) among young adults in Taiwan. Studies of the infectious complications and outcomes among such SLE patients undergoing peritoneal dialysis (PD) are limited. A retrospective age- and gender-matched case control study. A university teaching hospital. There were 23 SLE patients with ESRD receiving PD for more than 3 months during the past 15 years. Another 46 age- and gender-matched non-SLE nondiabetic patients receiving PD were selected as the control group in this study. All patients underwent PD as renal replacement therapy and were regularly followed up at this hospital. Technique survival and incidences of exit-site infection (ESI) and peritonitis in these patients. The SLE patients had a lower predialysis serum albumin than the control group (3.16 +/- 0.50 g/dL vs 3.52 +/- 0.50 g/dL, p < 0.01). The incidences of exit-site infection (ESI) and peritonitis were higher for SLE patients than for control patients (p < 0.01 and p < 0.001, respectively). Kaplan-Meier survival analysis indicated that SLE patients had shorter time intervals to first infectious complications, and poorer technique survival. Infec...Continue Reading

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