Systemic lupus erythematosus, rheumatoid arthritis, and postarthroplasty mortality: a cross-sectional analysis from the nationwide inpatient sample

The Journal of Rheumatology
Robyn T DomsicEswar Krishnan

Abstract

Systemic lupus erythematosus (SLE) is a disease of considerable morbidity, and this may place patients at greater risk for poor in-hospital postoperative outcomes for procedures such as arthroplasty. Our aim was to test this hypothesis. We compared the in-hospital postoperative mortality risk for patients with SLE undergoing hip and knee arthroplasty to those with rheumatoid arthritis (RA) and the general population without either condition, using data from the Nationwide Inpatient Sample (1993-2006). We performed parallel, weighted, multivariable logistic regressions to calculate mortality risk stratified by joint site, type of admission, hospital type, income category, race, length of stay, surgical indication, and medical comorbidities. The unadjusted mortality rates (per 1000 procedures) for patients with SLE, patients with RA, and controls were 7.4, 3.0, and 6.5, respectively, for nonelective procedures and 2.4, 1.3, and 1.8 for elective procedures. After adjustment for potential confounders, patients with SLE had an OR of 4.0 (95% CI 1.9-8.0) for postoperative mortality with hip replacements and an OR of 1.2 (95% CI 0.2-7.5) for mortality with knee replacements. Mortality risk of patients with RA was not different from th...Continue Reading

References

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Citations

Jul 28, 2013·Current Rheumatology Reports·Susan M Goodman, C Ronald Mackenzie
Nov 26, 2015·The Journal of Arthroplasty·Kimona IssaMichael A Mont
Dec 25, 2015·Best Practice & Research. Clinical Rheumatology·Susan M Goodman, Mark A Figgie
Jun 15, 2013·The Journal of Arthroplasty·Ottokar StundnerStavros G Memtsoudis
Jul 23, 2016·Current Rheumatology Reports·Shanthini Kasturi, Susan Goodman
Apr 3, 2014·The Journal of Rheumatology·Christina Mertelsmann-VossLisa A Mandl
Sep 24, 2016·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Arielle W FeinSusan M Goodman
May 15, 2013·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Susan M Goodman
Feb 17, 2021·The Medical Clinics of North America·Diane Zisa, Susan M Goodman

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