PMID: 3506091Apr 1, 1987Paper

Systemic mastocytosis in 16 dogs

Journal of Veterinary Internal Medicine
D A O'KeefeR M Jacobs

Abstract

The clinical and pathologic features of systemic mastocytosis in 16 dogs are reported. There was no apparent breed or sex predilection, and the median age at presentation was 9.5 years. In 14 of 16 cases there was a primary cutaneous mast cell tumor (MCT). When cutaneous tumor location was compared with previous reports, there was no association between location and systemic dissemination. The most common presenting signs associated with the cutaneous tumor were regional dissemination, edema, ulceration, and abscessation. They were present in 12 dogs (69%). Signs of systemic illness, including anorexia, vomiting, and diarrhea, were seen in eight dogs (50%). Other than the cutaneous tumors, the most consistent physical and radiographic abnormalities included lymphadenopathy, splenomegaly, and hepatomegaly. Eosinophilia and basophilia were seen in two and five dogs, respectively. Six dogs had increased numbers of mast cells in peripheral blood or buffy coat smears. Five of the nine dogs evaluated had increased numbers of mast cells in bone marrow aspirates. Bone marrow aspiration was superior to both peripheral blood and buffy coat smears in predicting mastocytosis. Coagulation abnormalities were seen in three of five dogs tested...Continue Reading

References

Aug 30, 1979·The New England Journal of Medicine·N A SoterS I Wasserman
Feb 1, 1977·The Veterinary Clinics of North America·P W Hess
Mar 1, 1985·Pathology, Research and Practice·M R ParwareschK Lennert
Jul 1, 1985·The Veterinary Clinics of North America. Small Animal Practice·D W Macy
Jan 1, 1973·The Journal of Small Animal Practice·D E Bostock
Oct 1, 1967·Archives of Dermatology·M Orkin
Apr 1, 1967·Zentralblatt für Veterinärmedizin. Reihe A·G H Hottendorf, S W Nielsen
Jan 1, 1968·Pathologia Veterinaria·G H Hottendorf, S W Nielsen
Sep 1, 1984·Veterinary Pathology·Amiya K PatnaikE G MacEwen
Nov 1, 1958·The British Journal of Dermatology·K W HEAD
Jan 1, 1965·Pathologia Veterinaria·G H HottendorfA J Kenyon
Jan 1, 1986·Veterinary Clinical Pathology·S L StockhamD A Schmidt

Citations

Mar 21, 2001·Australian Veterinary Journal·D Tyrrell, R M Davis
Jan 1, 1997·Veterinary Clinical Pathology·D. WalkerK. D. Clinkenbeard
Nov 19, 2011·Veterinary Clinical Pathology·Inger Lilliehöök, Harold W Tvedten
Feb 21, 1998·Journal of Veterinary Internal Medicine·D L McCawJ C Johnson
Jun 20, 2008·Journal of Veterinary Internal Medicine·L MarconatoE Zini
Aug 7, 2009·Journal of Veterinary Internal Medicine·D StefanelloM Caniatti
Feb 5, 2008·American Journal of Veterinary Research·Daniel A FeeneyRobert M Hardy
Dec 7, 2007·Journal of the American Veterinary Medical Association·Laura D GarrettRuthanne Chun
Jan 23, 2004·Journal of the American Animal Hospital Association·Michele SteffeyBradley L Njaa
Jan 25, 2005·The Veterinary Quarterly·W Misdorp
Jan 31, 2012·The Veterinary Clinics of North America. Small Animal Practice·Michael O Childress
Jun 16, 2009·The Veterinary Clinics of North America. Small Animal Practice·Cheryl Balkman
Apr 4, 2008·Journal of Comparative Pathology·D FewsI A Battersby
Nov 5, 2008·Veterinary Dermatology·Monika M WelleSilvia Rüfenacht
Jun 15, 2007·The Journal of Small Animal Practice·J M Dobson, T J Scase
Jun 22, 2011·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Alison P BookJohn Mattoon
Feb 9, 2010·The Journal of Small Animal Practice·C ElwoodK Savary-Bataille
May 27, 2010·Veterinary Ophthalmology·Elsa BeltranVictoria Johnson
Jul 11, 2003·The Veterinary Clinics of North America. Small Animal Practice·Cheryl A London, Bernard Seguin
Mar 17, 2000·The Journal of Veterinary Medical Science·Y HikasaH Matsuda
Dec 4, 2014·Critical Reviews in Oncology/hematology·Girolamo RanieriRaffaele Luigi Sciorsci
Jan 1, 1995·The Veterinary Clinics of North America. Small Animal Practice·D Ruslander, R Page
Jan 1, 1989·The Veterinary Clinics of North America. Small Animal Practice·W B Morrison
Jul 1, 1989·The Veterinary Clinics of North America. Small Animal Practice·K S Latimer, P M Rakich
Jan 1, 1988·The Veterinary Clinics of North America. Small Animal Practice·D A O'Keefe, C G Couto
Jul 1, 1990·The Veterinary Clinics of North America. Small Animal Practice·D A O'Keefe
Jul 1, 1995·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·D M Miller
Aug 23, 2006·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Lauretta TurinFederica Riva
Jun 10, 2004·The Journal of Veterinary Medical Science·Haruhiko MaruyamaAtsuhiko Hasegawa
Sep 1, 2007·Veterinary and Comparative Oncology·M A Camps-PalauPhilip J Bergman
Jan 29, 2000·Journal of the American Veterinary Medical Association·T TakahashiN Sasaki
Apr 23, 2005·Journal of the American Veterinary Medical Association·Gabriella SfiligoiTracy L Gieger
Jan 24, 2006·Journal of the American Veterinary Medical Association·Ryan P FulcherAmiya K Patnaik
Feb 1, 1993·Zeitschrift Für Lebensmittel-Untersuchung Und -Forschung·K HimbergK Louekari
Jan 24, 2002·Journal of the American Animal Hospital Association·Lisa E MooreDavid S Biller
Mar 10, 2004·Journal of the American Animal Hospital Association·David R DaviesPeter J Irwin
Nov 10, 2020·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Alexander AceinoCarolyn L Hodo

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.