PMID: 8592810Nov 1, 1995Paper

Systemic mastocytosis in a goat

Veterinary Pathology
K N KhanK Tanaka

Abstract

Systemic mastocytosis was diagnosed in a 4-year-old, female Nubian goat. Clinically, the animal was depressed and had severe macrocytic hypochromic anemia and leukopenia. Postmortem examination revealed neoplastic mast cells invading the heart, lung, liver, spleen, lymph nodes, and bone marrow. Eosinophils were frequently admixed with infiltrating mast cells in all organs. Using routine light microscopy, histochemistry, and transmission electron microscopy, metachromatic and periodic acid-Schiff-positive granules were identified within the cytoplasm of neoplastic mast cells. Erythrophagocytosis was observed in some neoplastic cells, although its contribution to the anemia was not clear. This report represents the first description of mast cell neoplasia in the goat.

References

Jan 1, 1976·Veterinary Pathology·A J Zubaidy
Jan 1, 1972·Veterinary Pathology·A C Johnstone

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Citations

May 17, 2008·Avian Pathology : Journal of the W.V.P.A·S Hafner, K Latimer
Sep 3, 2010·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Tzu-Yin LinPaul Stromberg
Oct 28, 2019·Veterinary Medicine and Science·Vanessa S TamlinAnne E Peaston
Nov 27, 2001·The Veterinary Record·N Allison, D L Fritz
Feb 6, 2021·The Veterinary Clinics of North America. Food Animal Practice·Jennifer Johns, Meera Heller

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