[Systemic therapy of malignant adrenal tumors].

Der Urologe. Ausg. A
M HorstmannM Kuczyk

Abstract

Systemic treatment of advanced-stage adrenal malignancies is most often only palliative. Mitotane alone or in combination with other chemotherapeutic agents such as cisplatin, etoposide, and vincristine are established therapeutic concepts for the treatment of metastatic adrenal cancer. Suramin and gossypol are rarely employed. New therapeutic options are tumor vaccination and treatment with antiangiogenic drugs. Metaiodobenzylguanidine as a radiotherapeutic drug or chemotherapeutic combination therapies that include cyclophosphamide, vincristine, and dacarbazine are applied for systemic treatment of malignant pheochromocytomas.. However, the clinical efficacy of the latter regimen needs further evaluation.

References

Apr 26, 1990·The New England Journal of Medicine·J P LutonP Blondeau
Aug 1, 1990·The Journal of Clinical Endocrinology and Metabolism·R V La RoccaC E Myers
Apr 1, 1989·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·C A SteinC E Myers
May 1, 1985·Hypertension·H R KeiserS D Averbuch
Mar 5, 1973·JAMA : the Journal of the American Medical Association·J A LubitzR Okun
Sep 1, 1994·Clinical Endocrinology·W ArltB Allolio
Jan 1, 1993·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·R M BukowskiW G Harker
Apr 1, 1993·The Journal of Clinical Endocrinology and Metabolism·M R FlackM M Reidenberg
May 1, 1997·The Journal of Clinical Endocrinology and Metabolism·A C Latronico, G P Chrousos
Aug 10, 1999·American Journal of Clinical Oncology·J C SissonS Spaulding
Dec 6, 2000·Annals of Oncology : Official Journal of the European Society for Medical Oncology·T S KhanB Eriksson
Oct 17, 2002·Annals of the New York Academy of Sciences·James C Sisson
Nov 30, 2002·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Michael Le BlancJudith A Smith
Mar 27, 2003·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·E Edström ElderB Hamberger
Oct 23, 2003·Endocrine Reviews·Helen E TurnerJohn A H Wass

❮ Previous
Next ❯

Related Concepts

Related Feeds

Angiogenesis Inhibitors to Treat Cancer

Cancer treatments including angiogenesis inhibitors prevent tumor cells from receiving nutrients and oxygen. Here is the latest research on angiogenesis inhibitors for the treatment of cancer.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

African Trypanosomiasis

African trypanosomiasis, also known as sleeping sickness, is an insect-borne parasitic disease of humans and other animals. It is caused by protozoa of the species Trypanosoma brucei and almost invariably progresses to death unless treated. Discover the latest research on African trypanosomiasis here.

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Related Papers

Journal of Cancer Research and Clinical Oncology
D KopfH Lehnert
Expert Opinion on Pharmacotherapy
Marko B Lens, Tim G Eisen
Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association
T DeutschbeinS Petersenn
© 2022 Meta ULC. All rights reserved