Systemic thermotherapy: description of a method and physiologic tolerance in clinical subjects
A safe, effective method of inducing total body hyperthermia to 42 degrees C (108 degrees F) has been developed and applied to clinical subjects with advanced malignancy. Physiological and biochemical parameters have been studied to determine tolerance and detect toxicity. Treatments were well tolerated with appropriate life support measures, mainly fluid and electrolyte replacement. Occasional arrhythmias and superficial cutaneous burns were the major complications. No evidence of central nervous system dysfunction was detected. Serum enzyme elevations after treatment appeared to indicate hepatic cellular injury but no clinical problems resulted. Renal, pulmonary, and hematologic parameters showed no significant changes from baseline values. Two early deaths occurred in patients with massive liver replacement with tumor and such patients may not be appropriate subjects for hyperthermia.
Percutaneous venovenous perfusion-induced systemic hyperthermia for advanced non-small cell lung cancer: initial clinical experience
Reconstruction of the temperature field for inverse ultrasound hyperthermia calculations at a muscle/bone interface
Protective effect of NG-monomethyl-L-arginine against hypotension inducted by combined tumour necrosis factor-alpha and whole body hyperthermia in rats
Towards the estimation of three-dimensional temperature fields from noisy temperature measurements during hyperthermia
Whole-body hyperthermia combined with hyperfractionated irradiation of the thorax in dog: acute physiological response
Attempt to induce total-body hyperthermia by whole-abdominal hyperthermia using a radiofrequency capacitive-heating system: an experimental study in dogs
Uniform regional heating of the lower trunk: numerical evaluation of tumor temperature distributions
Treatment of peritoneal carcinomatosis with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: state of the art and future developments
Temperature elevation during brachytherapy for carcinoma of the uterine cervix: adverse effect on survival and enhancement of distant metastasis
A study of the effect of sensor placement and perfusion pattern variations on thermal tomography solutions in hyperthermia
Percutaneous venovenous perfusion-induced systemic hyperthermia for lung cancer: a phase I safety study
Hyperthermic effects on peripheral lymphocytes isolated from a chronic lymphocytic lymphoma/leukemia patient in vitro
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