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Systems medicine and metabolic modelling

Journal of Internal Medicine

Dec 7, 2011

Adil Mardinoglu, Jens Nielsen

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Abstract

Several complex diseases are caused by the malfunction of human metabolism, and deciphering the underlying molecular mechanisms can elucidate their aetiology. Systems biology is an integrative approach combining experimental and computational biology to identify and describe the molecul...read more

Mentioned in this Paper

Metabolic Process, Cellular
In Silico
Biochemical Pathway
Enzymes, antithrombotic
Metabolic Networks
Etiology
Metabolic Pathway
Enzymes for Treatment of Wounds and Ulcers
Individualized Medicine
Computational Biology
Paper Details
References
  • References76
  • Citations52
12345...
  • References76
  • Citations52
12345...

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Systems medicine and metabolic modelling

Journal of Internal Medicine

Dec 7, 2011

Adil Mardinoglu, Jens Nielsen

PMID: 22142312

DOI: 10.1111/j.1365-2796.2011.02493.x

Abstract

Several complex diseases are caused by the malfunction of human metabolism, and deciphering the underlying molecular mechanisms can elucidate their aetiology. Systems biology is an integrative approach combining experimental and computational biology to identify and describe the molecul...read more

Mentioned in this Paper

Metabolic Process, Cellular
In Silico
Biochemical Pathway
Enzymes, antithrombotic
Metabolic Networks
Etiology
Metabolic Pathway
Enzymes for Treatment of Wounds and Ulcers
Individualized Medicine
Computational Biology

Feeds With Similar Papers

Precision Medicine

Precision medicine is a medical model that proposes the customization of healthcare, with medical decisions, treatments, practices, or products being tailored to the patient traits and specific molecular features of disease processes. In this model, diagnostic testing is often employed for selecting appropriate and optimal therapies based on the context of a patient’s genetic content or other molecular or cellular analysis. Tools employed in precision medicine can include molecular diagnostics, imaging, and analytics

Structural Biology: Biophysics

Structural Biology: Biophysics describes the study of structural biology using various biophysical techiniques such as imaging, computational modeling, etc. Discover the latest research on structrual biology here.

Related Papers

Biotechnology Journal

Genome-scale modeling of human metabolism - a systems biology approach

Biotechnology JournalApril 25, 2013
Adil MardinogluJens Nielsen
Paper Details
References
  • References76
  • Citations52
12345...
  • References76
  • Citations52
12345...

Download from

Publisher
PubMed
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