PMID: 3759268Sep 1, 1986Paper

Systolic compression of coronary artery in hypertrophic cardiomyopathy

International Journal of Cardiology
F Navarro-LopezA Betriu

Abstract

To determine the prevalence and significance of the systolic compression of the anterior descending coronary artery in hypertrophic cardiomyopathy, we studied 54 consecutive patients out of a catheterization laboratory population of 1619. This angiographic finding was found to be more prevalent (P less than 0.001) and severe in myopathic than in secondary hypertrophy. Complete systolic occlusion occurred in 5 of the 6 patients with nonobstructive cardiomyopathy showing the systolic narrowing. Severe septal squeezing was also present in these cases and the diastolic time lag to refill the distal branches reached 20-33% of the diastolic period. This subset of patients showed the least dynamic anterior wall contraction (P less than 0.001) and the highest incidence of thallium-201 perfusion defects (P less than 0.05) and of recurrent cardiac arrest (P less than 0.05). We conclude that severe systolic compression of the descending coronary artery in hypertrophic cardiomyopathy may be an angiographic marker of the myopathic hypertrophy extending to the anterior wall and might contribute to ischemia when the time to restore the distal perfusion is greatly delayed.

References

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Citations

Nov 28, 2002·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Vijay G KalariaJeffrey A Breall
Feb 15, 2008·Heart and Vessels·Robert F BonviniUlrich Sigwart
Jan 23, 2009·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Gunnar PlehnHans-Joachim Trappe
Feb 11, 2003·Journal of the American College of Cardiology·Martial G BourassaJean-Claude Tardif
Sep 6, 2003·Journal of the American College of Cardiology·Paul SorajjaDavid R Holmes
Oct 22, 1998·The New England Journal of Medicine·A T YetmanR Gow
Jan 24, 2012·Journal of Cardiovascular Computed Tomography·Rine NakanishiDaniel S Berman
Jan 1, 1990·International Journal of Cardiology·S S FurnissC G McGregor
Mar 22, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Dian WangNai Feng Liu
Mar 15, 2005·European Heart Journal·Jorge R AlegriaCharanjit S Rihal
Sep 1, 1989·Catheterization and Cardiovascular Diagnosis·K T Minami, D J Fergusson
Apr 20, 2000·Indian Journal of Pediatrics·S B JureidiniP S Rao

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