PMID: 11316132Apr 24, 2001Paper

Systolic dysfunction and blood pressure responses to supine exercise in patients with hypertrophic cardiomyopathy

Japanese Circulation Journal
M ShimizuH Mabuchi

Abstract

Left ventricular function and blood pressure responses were evaluated in 56 patients with non-obstructive hypertrophic cardiomyopathy (HCM) and 12 control subjects by using a radionuclide ventricular function monitor during supine ergometer exercise. Patients with HCM were divided into 2 groups: (i) group A had no decrease in ejection fraction (EF) during exercise; and (ii) group B had a decrease in EF during exercise. During exercise, the change in end-diastolic volume did not differ between the 3 groups. In contrast, the change in end-systolic volume differed between the 3 groups (p<0.0001). The change in systolic blood pressure (SBP) also differed significantly between the 3 groups. The change in SBP in group B was smaller than that in the control group and group A, and changes in the EF and changes in the SBP between rest and peak exercise showed a significant correlation (p<0.005). These results suggest that exercise-induced systolic dysfunction in patients with non-obstructive HCM may contribute to abnormal blood pressure response in those patients.

References

Jun 1, 1979·The American Journal of Cardiology·B J Maron, S E Epstein
Mar 1, 1992·Journal of the American College of Cardiology·T ChikamoriW J McKenna
Sep 1, 1995·British Heart Journal·H ThomsonM Frenneaux
Dec 19, 1998·Journal of the American College of Cardiology·N YoshidaT Imaizumi

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Citations

Dec 6, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Jesús PeteiroAlfonso Castro-Beiras

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