PMID: 6979041Mar 1, 1982Paper

T- and B-lymphocyte count of thyroid pathology patients

Problemy e̊ndokrinologii
A V Epishin

Abstract

Absolute and relative content of the peripheral blood T-, B- and "zero" cells was studied in 204 patients with thyroid pathology (154 subjects with toxic and 32 with non-toxic goiter, 12 with hypothyrosis and 6 with Hashimoto thyroiditis) by means of spontaneous and complementary rosette-forming method. Patients, suffering from thyroid diseases, mainly from moderate and severe goiter, hypothyrosis and Hashimoto goiter, developed changes in T- and B-lymphocyte system, manifesting in significant fall of the blood absolute and relative T-cell number and B-lymphocyte count increase. Frequency and extent of these alterations depend on severity of toxic goiter, ophthalmopathy and chronic infection presence. T- and B-lymphocyte system does not return to normal in the nearest periods after the drug treatment.

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