PMID: 6983072Nov 1, 1982Paper

T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood

Proceedings of the National Academy of Sciences of the United States of America
R J AlbertiniW R Borcherding

Abstract

Rare thioguanine-resistant T lymphocytes, present in vivo in human peripheral blood, were isolated and grown in vitro as thioguanine-resistant cultured T cells. The conditions for their selection in vitro were such that thioguanine resistance had to have arisen in vivo. The mutant cells bore T-cell surface markers, maintained their thioguanine resistance in vitro in the presence or absence of selection, and were deficient in hypoxanthine-guanine phosphoribosyltransferase activity.

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Apr 1, 1964·The American Journal of Medicine·M LESCH, W L NYHAN

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Citations

Nov 1, 1995·Genes, Chromosomes & Cancer·P HackmanB Lambert
Jan 1, 1997·Stem Cells·M Goldman
Jan 1, 1990·Teratogenesis, Carcinogenesis, and Mutagenesis·S De Flora
Jun 1, 1988·Cell Biology and Toxicology·M S TurkerG M Martin
Sep 1, 1995·Somatic Cell and Molecular Genetics·I R RainvilleJ A Nicklas
Jan 1, 1994·Somatic Cell and Molecular Genetics·J C FuscoeG Pilia
Jun 1, 1990·Aging : Clinical and Experimental Research·J Vijg
Apr 15, 1988·Clinica Chimica Acta; International Journal of Clinical Chemistry·K AdolphF F Snyder
Dec 1, 1987·Mutation Research·P H LohmanF Berends
Aug 1, 1987·Mutation Research·T FeatherstoneH J Evans
Mar 1, 1988·Mutation Research·M JanatipourA A Morley
Sep 1, 1988·Mutation Research·M HakodaM Otake
Jan 1, 1989·Mutation Research·M HakodaM Akiyama
Apr 1, 1992·Mutation Research·S A GristA A Morley
Jan 1, 1993·Mutation Research·J L DempseyA A Morley
Jan 1, 1995·Mutation Research·M J LippertJ A Nicklas
Jul 16, 1994·Mutation Research·J VijgE Mullaart

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