T-cell immunotherapy of tumors by adoptive transfer of cytotoxic T lymphocytes and by vaccination with minimal essential epitopes

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T-cell immunotherapy of tumors by adoptive transfer of cytotoxic T lymphocytes and by vaccination with minimal essential epitopes

Abstract

References

Glycosaminoglycans in thyroid-associated ophthalmopathy

Tumor eradication by adoptive transfer of cytotoxic T lymphocytes

Human papillomaviruses in the pathogenesis of anogenital cancer.

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

In vivo efficacy of virus-derived peptides and virus-specific cytotoxic T lymphocytes.

Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide

Adoptive T cell therapy of tumors: mechanisms operative in the recognition and elimination of tumor cells

Peptide-induced antiviral protection by cytotoxic T cells.

Eradication of adenovirus E1-induced tumors by E1A-specific cytotoxic T lymphocytes

Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein.

Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines

Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report

Biology and biochemistry of papillomaviruses

Human leukocyte antigen-A2.1 restricted candidate cytotoxic T lymphocyte epitopes of human papillomavirus type 16 E6 and E7 proteins identified by using the processing-defective human cell line T2

Limitations of predictive motifs revealed by cytotoxic T lymphocyte epitope mapping of the human papilloma virus E7 protein

Identification of an H-2 Kb-presented Moloney murine leukemia virus cytotoxic T-lymphocyte epitope that displays enhanced recognition in H-2 Db mutant bm13 mice

Detailed motifs for peptide binding to HLA-A*0201 derived from large random sets of peptides using a cellular binding assay

Mutant oncopeptide immunization induces CTL specifically lysing tumor cells endogenously expressing the corresponding intact mutant p53

A "string-of-beads" vaccine, comprising linked minigenes, confers protection from lethal-dose virus challenge

Vaccination with cytotoxic T lymphocyte epitope-containing peptide protects against a tumor induced by human papillomavirus type 16-transformed cells

Efficient MHC class I-peptide binding is required but does not ensure MHC class I-restricted immunogenicity

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

Interleukin 12: a key modulator of immune function

Decrease of extracellular catecholamine content in the vicinity of cortical penicillin-induced epileptogenic focus: voltammetric study in the rat

p53, a potential target for tumor-directed T cells

Two tyrosinase nonapeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes

Potential immunogenicity of oncogene and tumor suppressor gene products

In vitro induction of human cytotoxic T lymphocyte responses against peptides of mutant and wild-type p53

Strict peptide length is not required for the induction of cytotoxic T lymphocyte-mediated antiviral protection by peptide vaccination

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

Citations

Adoptive immunotherapy prevents prostate cancer in a transgenic animal model

Heat shock protein 70/MAGE-3 fusion protein vaccine can enhance cellular and humoral immune responses to MAGE-3 in vivo

MAGE-1/Heat shock protein 70/MAGE-3 fusion protein vaccine in nanoemulsion enhances cellular and humoral immune responses to MAGE-1 or MAGE-3 in vivo

Preventive and therapeutic vaccination with PAP-3, a novel human prostate cancer peptide, inhibits carcinoma development in HLA transgenic mice

The antitumor immune responses induced by nanoemulsion-encapsulated MAGE1-HSP70/SEA complex protein vaccine following peroral administration route

In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC).

Enhancement of DNA vaccine potency through linkage of antigen gene to ER chaperone molecules, ER-60, tapasin, and calnexin

An artificial solution for adoptive immunotherapy

Generation of high quantities of viral and tumor-specific human CD4+ and CD8+ T-cell clones using peptide pulsed mature dendritic cells

Application of multicolor fluorescence in situ hybridization analysis for detection of cross-contamination and in vitro progression in commonly used murine tumor cell lines

Improvement of the enzymatic stability of a cytotoxic T-lymphocyte-epitope model peptide for its oral administration

B7-mediated costimulation and the immune response

T cell infiltration and MHC I and II expression in the presence of tumor antigens: An immunohistochemical study in patients with serous epithelial ovarian cancer

Peptide-based cancer vaccines

Immunodeficiency and cancer: prospects for correction

Cross-presentation of tumour antigens: evaluation of threshold, duration, distribution and regulation

The use of vaccines in treating cervical cancer: present status and future prospects