PMID: 6974867Jul 1, 1981Paper

T cells may express multiple activities: specific allohelp, cytolysis, and delayed-type hypersensitivity are expressed by a cloned T-cell line

Proceedings of the National Academy of Sciences of the United States of America
G DennertJ F Warner

Abstract

A T-cell line that recognizes private specificities encoded in the H-2 IA subregion in the proliferative response, cytotoxic activity, delayed-type hypersensitivity, and allohelp reaction with B cells has been cloned. The individual clones were assayed for ability to express the activities of the parent line. Results show that the cloned sublines tested are able to perform all the activities of the parent line. It is suggested that T cells may express multiple activities and that the apparent monofunctionality of T cells is due to regulation of these activities.

Citations

Jul 30, 1982·Journal of Immunological Methods·W Haas, H Von Boehmer
Dec 1, 1984·Human Immunology·C Rohowsky-KochanN Suciu-Foca
Dec 1, 1987·Immunology and Cell Biology·D McKinnon, P D Hodgkin
Dec 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·T LeandersonA Coutinho
Jun 1, 1982·The Journal of Experimental Medicine·C Spellman, R E Anderson
Oct 1, 1983·The Journal of Experimental Medicine·J L PlattA F Michael
Feb 1, 1984·The Journal of Experimental Medicine·L AndrusE Reich
Sep 1, 1991·Medical Hypotheses·B Daunter
Jan 1, 1982·Immunological Reviews·S L SwainR W Dutton
Jan 1, 1984·Immunological Reviews·B M Hall, S E Dorsch
Oct 1, 1984·Immunological Reviews·J Forman
Sep 1, 1988·Scandinavian Journal of Immunology·K Eichmann
Jan 1, 1997·International Reviews of Immunology·G Dennert

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