T helper cell differentiation: understanding the needs of hierarchy

Immunity
Thomas Weichhart, Marcus D Säemann

Abstract

In this issue of Immunity, Lee et al. (2010) demonstrate that the mammalian Target of Rapamycin Complex 2 promotes the differentiation of T helper 1 (Th1) cells via the kinase Akt, whereas it independently fosters Th2 cell generation via another kinase, PKC-theta.

Citations

Jul 20, 2019·BMC Biology·Pundrik Jaiswal, Alan R Kimmel
Aug 28, 2021·International Journal of Molecular Sciences·Laura PasseriSilvia Gregori

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