T-lymphocyte reactivity during the menstrual cycle in women

Clinical Immunology and Immunopathology
A R CaggiulaB S Rabin

Abstract

Reactivity of blood lymphocytes to nonspecific mitogenic stimulation with phytohemagglutinin (PHA) was measured in nine healthy, regularly cycling women at three phases of their menstrual cycles corresponding to peak levels of estradiol (midfollicular phase), peak levels of progesterone (midluteal phase), and the lowest levels of both hormones (menstrual phase). Sampling points were verified by radioimmunoassay of estrogen, progesterone, luteinizing hormone, and follicle-stimulating hormone. There were significant increases in reactivity associated with an increasing concentration of PHA and with autologous plasma vs AB plasma. However, no differences were found in reactivity to PHA over the three menstrual cycle phases and correlational analyses indicated no relationship between counts and any of the hormones measured.

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References


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Citations

Jan 1, 1996·International Journal of Behavioral Medicine·L RedwineA Baum
Aug 10, 2001·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·S G WestK M Emmons
Apr 16, 2019·Frontiers in Endocrinology·Nishel M ShahMark R Johnson
Jul 6, 2018·Frontiers in Immunology·Nishel M ShahMark R Johnson
Jun 13, 2003·The Neurologist·Barbara S Giesser

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