PMID: 8598360Mar 1, 1996Paper

T1 and T2 squamous cell carcinomas of the floor of the mouth: results of brachytherapy mainly using 198Au grains

International Journal of Radiation Oncology, Biology, Physics
S MatsumotoS Suzuki

Abstract

To investigate the effectiveness of brachytherapy provided by this institution over a 25-year period, and to specifically verify the efficacy of 198Au grain therapy, this study evaluated the outcomes in patients given brachytherapy for T1 and T2 squamous cell carcinoma (SCCs) of the floor of the mouth. A retrospective analysis of data from 90 patients with T1 and T2 SCCs of the floor of the mouth who underwent brachytherapy between 1965 and 1989. Therapy mainly consisted of 198Au grain implants with or without external irradiation. As for the brachytherapeutic source, 15 patients were treated with radon seeds, 60 with 198Au grains, 10 with radium needles, 3 with cobalt needles, and 2 with iridium hairpins. Based on the 1987 International Union Against Cancer (UICC) classification, the SCC stagings and number of cases per staging follow: Stage I (T1N0), 21 cases; Stage II (T2N0), 55 cases; and Stage III-IV (T1-2N1-2), 14 cases. The minimum follow-up time was 3 years. The local control rates of these SCCs, based on tumor size, were 89% for T1 lesions, 76% for T2a (< or = 3 cm) lesions, and 56% for T2b (> 3 cm) lesions, and 82% for T1-2 lesions without a gingival involvement, in contrast to 55% for lesions with a gingival involvem...Continue Reading

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Citations

Feb 20, 2009·International Journal of Clinical Oncology·Hitoshi Shibuya
Apr 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Hugo MarsigliaAlain Gerbaulet
May 20, 1998·International Journal of Radiation Oncology, Biology, Physics·T InoueH Fuchihata
Mar 8, 2016·Brachytherapy·Harjot Kaur BajwaKrishnam Raju Alluri
Aug 5, 2008·International Journal of Radiation Oncology, Biology, Physics·Ryo-ichi YoshimuraKazuma Toda
Nov 22, 2011·International Journal of Radiation Oncology, Biology, Physics·Ryo-Ichi YoshimuraMasahiko Miura
Nov 11, 2006·Japanese Journal of Clinical Oncology·Seiko Nishioka, Takeshi Nishioka
Jul 20, 2011·Journal of Radiation Research·Abulajiang TayierRyoichi Yoshimura

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