T1rho and T2 relaxation times of the normal adult knee meniscus at 3T: analysis of zonal differences

BMC Musculoskeletal Disorders
Shoichiro TakaoHiroshi Yoshioka

Abstract

Prior studies describe histological and immunohistochemical differences in collagen and proteoglycan content in different meniscal zones. The aim of this study is to evaluate horizontal and vertical zonal differentiation of T1rho and T2 relaxation times of the entire meniscus from volunteers without symptom and imaging abnormality. Twenty volunteers age between 19 and 38 who have no knee-related clinical symptoms, and no history of prior knee surgeries were enrolled in this study. Two T1rho mapping (b-FFE T1rho and SPGR T1rho) and T2 mapping images were acquired with a 3.0-T MR scanner. Each meniscus was divided manually into superficial and deep zones for horizontal zonal analysis. The anterior and posterior horns of each meniscus were divided manually into white, red-white and red zones for vertical zonal analysis. Zonal differences of average relaxation times among each zone, and both inter- and intra-observer reproducibility were statistically analyzed. In horizontal zonal analysis, T1rho relaxation times of the superficial zone tended to be higher than those of the deep zone, and this difference was statistically significant in the medial meniscal segments (84.3 ms vs 76.0 ms on b-FFE, p < 0.0001 and 96.5 ms vs 91.7 ms on ...Continue Reading

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Citations

Jan 8, 2019·Journal of Magnetic Resonance Imaging : JMRI·Rahman BaboliRavinder R Regatte
Feb 14, 2020·Scientific Reports·Sven NebelungDaniel Truhn
Apr 25, 2018·Journal of Magnetic Resonance Imaging : JMRI·Kelly C McPhee, Alan H Wilman
Sep 5, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Nobutake OzekiIchiro Sekiya
Jul 11, 2021·Scientific Reports·William Fedje-JohnstonMarc Tompkins

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Methods Mentioned

BETA
electron microscopy

Software Mentioned

MedCalc
SPGR
Excel
Windows
PROSET
MIPAV ( Medical Image Processing , Analysis and Visualization )
Matlab
FFE

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