PMID: 16538206Mar 16, 2006Paper

T2-hyperintense foci on brain MR imaging

Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Monika Bekiesińska-Figatowska

Abstract

T2-hyperintense foci are one of the most frequent findings in cerebral magnetic resonance imaging (MRI). They can pose serious diagnostic problems which is reflected by their English name and abbreviation - UBOs (Unidentified Bright Objects). Cerebral MRI results of 246 patients (134 females, 112 males), aged 2 -79 years, were analyzed. The examinations were done with the 0.5 and 1.5 T MRI scanners. T1-, PD or FLAIR and T2-weighted images were obtained. Diffusion-weighted imaging (DWI) was also performed in a high field system. The following diagnoses were established: widened perivascular spaces in 11 cases, foci most probably associated with brain aging -21, with migraine -15, ischaemic changes -52, vasculitis -12, hypoxic-ischaemic changes -8, haemorrhagic foci -11, inflammatory changes -20, multiple sclerosis -50, central pontine and extrapontine myelinolysis -7, metastases -7, changes caused by radio-and chemotherapy - 8, lesions associated with neurometabolic diseases - 10, CNS degenerative diseases - 13, eclampsia - 1. MRI is a sensitive method of CNS focal lesions detection but is less specific as far as their differentiation is concerned. Particular features of the focal lesions on MR images (number, size, location, pr...Continue Reading

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