TACE combined with PEI versus TACE alone in the treatment of HCC: a meta-analysis.

Medical Oncology
Na WangYongxun Zhao

Abstract

To assess the evidence for improved outcomes in hepatocellular carcinoma (HCC) with transarterial chemoembolization (TACE) plus percutaneous ethanol injection (PEI). A systematic search of MEDLINE, EMBASE, the Cochrane library, Chinese biomedicine literature database, Chinese scientific full-text database, and Chinese journal full-text database was undertaken for relevant articles. The computer search was supplemented with a manual search of reference lists for all available review articles, primary studies, and books to identify other studies not found in the computer search. The initial search identified seven randomized trials that included 623 patients. Meta-analysis results are as follows: the 6-month, 1-, 2-, and 3-year survival rates were significantly better in patients with the TACE+PEI group than TACE group; in the decline rates of the AFP level and the reduction rates of tumor size (>50%), the TACE+PEI group has better effects than TACE group; as adverse effects, TACE+PEI group has lower incidence rates than TACE group. In patients with HCC, the efficacy of TACE combined with PEI is significantly better than that of TACE alone. Although there is convincing evidence to confirm the results mentioned, they still need to...Continue Reading

References

Dec 12, 2003·Lancet·Josep M LlovetJordi Bruix
Nov 8, 2005·World Journal of Gastroenterology : WJG·Gerhild BeckerHans-Peter Allgaier
Jun 17, 2006·Cardiovascular and Interventional Radiology·I Kaare TesdalChristoph Dueber
May 15, 2008·Journal of the National Cancer Institute·Josep M LlovetUNKNOWN Panel of Experts in HCC-Design Clinical Trials
Jan 23, 2009·The Cochrane Database of Systematic Reviews·Miny SamuelKhee-Chee Soo

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Citations

Oct 2, 2012·World Journal of Radiology·Ashwin RammohanPalaniappan Ravichandran
Oct 17, 2014·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Jiang-Hui CaoQing-Yun Long
Aug 8, 2015·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Surabhi BajpaiDushyant Sahani
Dec 11, 2014·World Journal of Gastroenterology : WJG·Li-Qun ZouYong-Song Guan
Mar 14, 2020·Medical Oncology·Matteo RenzulliRita Golfieri
May 29, 2015·World Journal of Hepatology·Giovan Giuseppe Di Costanzo, Raffaella Tortora

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