Tai-Kang-Ning, a Chinese herbal medicine formula, alleviates acute heroin withdrawal

The American Journal of Drug and Alcohol Abuse
Lin KangJing Li

Abstract

The efficacy and safety of Tai-Kang-Ning (TKN) capsule, a traditional Chinese medicine formula, for the treatment of acute heroin withdrawal syndrome were investigated by conducting a double-blind, double-dummy, positive-controlled, and randomized trial. Sixty-four patients with acute heroin withdrawal syndrome were recruited. These patients were treated with either TKN or lofexidine in a fixed schedule of doses for 10 days. The results indicate that both treatments significantly reduced withdrawal symptoms by day 3, but there was no significant difference overall between lofexidine and TKN in efficacy or safety. These results demonstrate that TKN is effective in the treatment of moderate-to-severe acute heroin withdrawal syndrome with mild adverse effects.

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Citations

May 18, 2011·Clinical and Experimental Pharmacology & Physiology·Hui SongSheng Zhong
Oct 21, 2009·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·David KieferKathryn Klunk
Apr 2, 2021·Journal of Integrative Medicine·Thomas EfferthDavid Y W Lee
May 22, 2021·Journal of Substance Abuse Treatment·Caroline KruszeckiKristina E Ward

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